食管癌前自然史观测及癌变风险分类  

The analysis of esophageal precancer natural law and cancerous risky classification

作　　者：白经修[1] 刘韵源[2] 白蓉 鲁照明[4] 

机构地区：[1]郑州大学消化疾病研究所,郑州450003 [2]中国医学科学院肿瘤所 [3]郑州铁路中心医院 [4]郑州大学医学院

出　　处：《胃肠病学和肝病学杂志》2002年第2期149-151,共3页Chinese Journal of Gastroenterology and Hepatology

基　　金：国家自然科学基金资助项目批准号 39770 832;河南省科委自然科学基金资助项目编号 2 0 0 0 4 0 2 350 0

摘　　要：目的　提高食管癌防治的效价比。方法　利用对我国当前食管癌防治方案的分析及食管癌前自然史观测。结果　应对食管上皮增生进行癌变风险分类 ,对不同癌变风险患者用不同方法处理 ,这是提高食管癌预防中效价比的有效方法。结论　选择γ -GT反应作为判定癌变风险大小的主要指标 ,是改变我国食管癌预防策略的一项重大改革。Aim To raise the ratio between the consumption and efficacity in the prevention of esophageal cancer.Methods The current prevention programmes and esophageal precancer natural law were analysed comprehensively.Results It was nec essary that the population with esophageal epithelial hyperplasia be divided on the basis of cancerogenic risk which was determined according to r GT reaction.Different means were used to treat subjects with different cancerogenic risk.It would be an effective method that raised the ratio between the efficacity and the consumption in esophageal cancerous prevention.Conclusions γ GT reaction is a significant marker to determine esophageal cancerous risk and its adoption is a great reform of preventive tactic in esophageal cancer.

关 键 词：癌变风险分类 食管癌 预防 Γ-谷氨酰转肽酶 

分 类 号：R735.1[医药卫生—肿瘤]