《中国实用眼科杂志》随机对照临床治疗试验文献方法学评价  

Methodological Evaluation of Randomized Controlled Clinical Therapeutic Trials Published in Chinese Journal of Practical Ophthalmology

作　　者：何为民[1] 吴晓梅[1] 唐莉[1] 杜江[1] 

机构地区：[1]四川大学华西医院眼科,四川成都610041

出　　处：《华西医学》2002年第2期150-151,共2页West China Medical Journal

摘　　要：目的 :了解《中国实用眼科杂志》从 1983年至 2 0 0 0年间随机对照临床治疗试验论文的设计和撰写现状。方法 :逐期逐页手工检索《中国实用眼科杂志》 1983～ 2 0 0 0年中发表的对照试验论文 ,按Cochrane协作网RCT、CCT资料库中的判定标准进行严格鉴定。结果 :在 18卷 194期中共刊登临床对照试验 16 6篇 (其中RCT78篇 ,CCT8篇 )。结论 :《中国实用眼科杂志》刊登的临床随机对照试验论文逐年增多 ,但仍存在较多问题 :没有做到真正的随机 ,试验组和对照组基线资料缺乏可比性 ,样本量太少 ,纳入、排除标准不明确 ,没有恰当的统计学分析。临床治疗试验的设计多采用RCT和盲法 ,并做到真正的随机。Objective:To study the quality of issues of randomized controlled trials published in Chinese Journal of Practical Ophthalmology from 1982 to 2000.Methods:It was checked over page-by-page the controlled trials of clinical therapeutic studies in Chinese Journal of Practical Ophthalmology from 1982 to 2000 to identify strictly randomized controlled trials (RCT) and Quasi-randomized control trials (CCT) according to the criteria of the handbook of Cochrane collabration in 1997.Result:A trial of 194 articles on clinical therapeutic trials was published in 194 issues covered 18 volumes of Chinese Journal of Practical Ophthalmology,among which,there were 78 issues of RCT and 8 issues of CCT.Conclusion:Randomized control trials published in Chinese Journal of Practical Ophthalmology were increased year-by-year.Many problems still exist and clinicians are urged to adopt RCT and blind trials and guarantee it to be a real RCTs.

关 键 词：《中国实用眼科杂志》 随机对照 文献评价 

分 类 号：R-5[医药卫生]