^(99m)Tc-MIBI断层显像对脑胶质瘤的诊断价值研究  

Research on single photon emission computed tomography imaging to brain gliomas with technetium^(99m) sestamibi

作　　者：钱伟东[1] 陈齐鸣[1] 

机构地区：[1]蚌埠医学院附属医院神经内科,233004

出　　处：《临床神经病学杂志》2002年第3期142-144,共3页Journal of Clinical Neurology

摘　　要：目的　探讨99mTc 甲氧基异丁基异腈 (MIBI)断层显像 (SPECT)对幕上脑胶质瘤的诊断价值。方法　 5 3例脑胶质瘤患者中 ,高度恶性脑胶质瘤 31例 ,低度恶性 2 2例 ,注射 740～ 930MBqMIBI 15分钟后行SPECT检查并重建冠状面、矢状面、横断面图像。MIBI的摄取指数计算为病灶区与对侧相同部位正常脑组织计数的比值。结果　高度恶性脑胶质瘤MIBI摄取指数为 1.9～ 6 .6 (平均 3.6± 1.4) ,低度恶性胶质瘤为 0 .8～1.7(1.1± 0 .2 ) ,两组比较P <0 .0 1。结论　99mTcObjective To explore the diagnosis value of single photon emission computed tomography(SPECT) imaging to supratentorial brain gliomas with technetium 99m sestamibi.Methods In 53 patients with supratentorial brain glioma,31 cases for high grade malignant glioma, 22 cases for low grade glioma were examined by SPECT,(SPECT was performed after injection 740-930 MBq MIBI for 15 min),and the coronal,sagittal and transverse views were reconstructed. MIBI uptake index was computed as the ratio of counts in foci region and the counts in contralateral homologous region.Results In high-grade malignant gliomas,the MIBI uptake index was 1.9～6.6(mean 3.6±1.4),low grade malignant gliomas was 0.8～1.7 (1.1±0.2),there is a comparison between the two groups(P<0.01).Conclusion MIBI SPECT imaging has certain clinical value in distinguishing high and low grade supratentorial gliomas in adults.

关 键 词：脑胶质瘤 SPECT 诊断 锝99M 

分 类 号：R739.41[医药卫生—肿瘤]