脑闩蛛网膜下腔微量注射青霉素G-K对脑干组织5─羟色胺含量的影响  

The effect of microinjection of penicillin G-K into arachnoid space at obex on the concentration of 5-HT in brain stem

作　　者：樊英显[1] 刘红娟[2] 孙宏晨[1] 

机构地区：[1]吉林大学口腔医院,130041 [2]吉林省人民医院口腔科

出　　处：《现代口腔医学杂志》2002年第4期318-319,共2页Journal of Modern Stomatology

摘　　要：目的　检测鼠三叉神经痛时脑干组织中 5 -羟色胺 (5 -HT)含量的变化。方法　建立鼠三叉神经痛动物模型 ,采用荧光分光光度法测定脑干组织中 5 -HT含量。结果　实验组脑干组织中 5 -HT含量明显低于正常组 (P <0 .0 1)。结论　三叉神经痛时 ,脑干组织中 5Objective Measure the changes of 5-HT of brain stem in rats with trigeminal neuralgia.Methods The animal model with trigeminal neuralgia was established in rats and the concentration of 5-HT of brain stem measured by fluorophotometry.Results The 5-HT of brain sterm in experimental group was significantly lower than the concentration of the control group(P< 0.01).Conclusion The concentration of 5-HT is clearly decreased in trigeminal neuralgia.

关 键 词：脑闩蛛网膜下腔微量注射 青霉素G-K 脑干组织 5-羟色胺 三叉神经痛 5-HT 

分 类 号：R745.11[医药卫生—神经病学与精神病学] R978.11[医药卫生—临床医学]