新型抗菌糊剂对感染根管内细菌杀灭作用的体内研究  

Disinfecting effects of a new polyantibiotic paste on infected root canal

作　　者：谭红[1] 叶玲[1] 胡涛[1] 李富明[1] 

机构地区：[1]四川大学华西口腔医学院,610041

出　　处：《实用口腔医学杂志》2002年第3期256-258,共3页Journal of Practical Stomatology

摘　　要：目的 :研究新型抗生素根管消毒糊剂 (甲硝唑 环丙沙星 二甲胺四环素 ,MCM )用于根管消毒的有效性和可行性。方法 :对 3 0例慢性根尖周炎或牙髓坏死患者进行随机分组 ,以甲酚醛为对照观察MCM的体内抑菌效果。结果 :甲酚醛与MCM的体内抑菌活性无统计学差异 ,尚不能认为MCM优于甲酚醛。结论 :MCM体内抗菌活性与甲酚醛无显著性差异 ,但刺激性小于后者 。Objective: To observe the antibacterial potential of a polyantibiotic paste MCM containing a mixture of metronidazole, ciprofloxacin and minomycin on infected root canal. Methods: MCM was applied in 12 cases with 12 root canal infected teeth and FC in 18 cases with 18 teeth. Antibacterial efficacy was evaluated in vivo by measuring bacterial recovery from the lesions Results: No predominant bacteria were recovered after the use of MCM; while only one of 4 kinds of predominant bacteria was observed in the group of FC( P >0.05). Conclusion: MCM may be useful in root canal therapy to disinfect the infected root canal.

关 键 词：新型抗菌糊剂 感染根管 细菌 杀灭作用 体内研究 消毒作用 

分 类 号：R781.34[医药卫生—口腔医学]