3476例眼眶占位性病变的组织病理学分类  

Histopathologic classification of 3 476 orbital diseases

作　　者：何彦津[1] 宋国祥[1] 丁莹[1] 

机构地区：[1]天津医科大学第二医院眼科,300211

出　　处：《中华眼科杂志》2002年第7期396-398,共3页Chinese Journal of Ophthalmology

摘　　要：目的　了解眼眶病组织病理学分类及分布状态。方法　对 1976～ 2 0 0 0年 3476例眼眶肿瘤手术切除标本进行病理学分类。结果　眼眶病病种有 10 0余种。良性肿瘤 2 84 7例 (81 90 % ) ,其中前 10位依次为海绵状血管瘤 5 15例 (18 0 9% ) ,静脉性血管瘤 36 4例 (12 79% ) ,炎性假瘤 347例(12 19% ) ,皮样囊肿 (表皮样囊肿 ) 2 30例 (8 0 8% ) ,神经鞘瘤 183例 (6 4 3% ) ,脑膜瘤 15 0例 (5 2 7% ) ,泪腺混合瘤 14 7例 (5 16 % ) ,黏液囊肿 14 1例 (4 95 % ) ,静脉曲张 132例 (4 6 4 % )及神经纤维瘤 76例(2 6 7% )。恶性肿瘤 6 2 9例 (18 10 % ) ,其中泪腺上皮性恶性肿瘤 12 9例 (2 0 5 1% ) ,横纹肌肉瘤 75例(11 92 % ) ,非霍奇金淋巴瘤 6 5例 (10 33% ) ,继发性副鼻窦癌 5 1例 (8 11% ) ,转移癌 5 0例 (7 95 % ) ,绿色瘤 32例 (5 0 9% ) ,视网膜母细胞瘤球外蔓延 2 6例 (4 13% ) ,脉络膜黑色素瘤球外蔓延 2 3例(3 6 6 % )。结论　眼眶病中最常见的疾病为脉管源肿瘤及血管畸形 ;眼眶原发恶性肿瘤主要为泪腺上皮性恶性肿瘤 ;纤维硬化型炎性假瘤病理形态不同于其他类型炎性假瘤 。Objective To investigate the histopathologic classification and distribution of orbital diseases Methods The authors analyzed 3 476 orbital diseases examined in 1976-2000 in the pathology laboratory Results Benign orbital diseases were 81 90% The 10 leading benign orbital diseases were cavernous hemangioma (515),vascular leiomyoma (364),inflammatory pseudotumor (347),dermoid (230),schwannoma (183),meningioma (150),benign mixed tumor of the lacrimal gland (147),mucocele (141),varix (132) and neurofibroma (76) Malignant orbital tumors were 18 10% The numbers of malignant tnmors were malignant lacrimal gland epithelial tumors (129, 20 51%), rhabdomyosarcoma (75), non Hodgkin′s disease (65), secondary to nasosinus carcinoma (51), metastatic tumor (50), chloroma (32), extraocular extension of retinoblastoma (26) and extraocular extension of choroid malanoma (23) Conclusions The vascular tumors and malformations are commonly seen in orbital diseases The primary malignant tumor in the orbit is the malignant lacrimal gland epithelial tumors

关 键 词：眼眶占位性病变 组织病理学 眶肿瘤 病理学 

分 类 号：R777.5[医药卫生—眼科]