老年性黄斑变性黄斑部脉络膜血循环研究  

Choriocapillaris circulatory study of macula in aging macular degeneration

作　　者：陈松[1] 韩梅[1] 王兰惠[1] 时冀川[1] 张树立[1] 

机构地区：[1]天津市眼科医院,300022

出　　处：《中华眼底病杂志》2002年第2期116-118,共3页Chinese Journal of Ocular Fundus Diseases

摘　　要：目的　探讨老年性黄斑变性 (aging macular degeneration,AMD)黄斑部脉络膜血循环改变。　方法　对 86例 AMD患者的 86只患眼 (其中渗出型 AMD患者 5 2例 5 2只眼 ,萎缩型 AMD患者 19例19只眼 ,黄斑玻璃疣患者 15例 15只眼 )以及正常对照者 2 7例 35只眼进行吲哚青绿血管造影 (indocya-nine green angiography,ICGA) ,对比观察黄斑部脉络膜血管充盈时间 (choriocapillaris filling phase,CFP)及脉络膜充盈情况。　结果　渗出型 AMD较正常对照组、萎缩型 AMD及黄斑玻璃疣眼的 CFP均显著延长 (P<0 .0 5 )。 86只 AMD患眼中有 4 0只眼 ICGA有局限性或广泛性脉络膜充盈不良或延迟 ,其中渗出型AMD2 4只眼 ,萎缩型 AMD12只眼 ,黄斑玻璃疣 4只眼。　结论　 AMD及黄斑玻璃疣患者黄斑部 CFP延长及脉络膜血管充盈异常。Purpose To discuss changes of macular choriocapillaris hemodynamics in AMD. Methods Eighty six eyes of 86 patients underwent ICGA,including macular drusen in 15 eyes of 15 patients,exudative AMD in 52 eyes of 52 patients,atrophic AMD in 19 eyes of 19 patients,for the observation of macular choriocapillaris perfusion. Results Choriocapillaris filling phase (CFP) of exudative AMD was obviously longer than that of eyes with normal, atrophic AMD and drusen groups ( P< 0.05). Forty eyes had local or extensive choroidal filling deficiency and prolongation, including 24 eyes of exudative AMD, 12 eyes of atrophic AMD,and 4 eyes of drusen group. Conclusion CFP of macula is prolonged and choriocapillaris perfusion is abnormal in AMD and macular drusen eyes.

关 键 词：老年性黄斑变性 黄斑变性 病理生理学 脉络膜 血液供给 吲哚花青绿 诊断 AMD 

分 类 号：R774.504[医药卫生—眼科]