脑腔隙性梗塞的定量研究  

To Investigate the Method for Measuring Lacunar Infarction Quantitatively

作　　者：王德治[1] 梁学军[2] 郭冀珍[1] 

机构地区：[1]上海第二医科大学瑞金医院高血压科,上海200025 [2]交通大学机械工程学院

出　　处：《上海第二医科大学学报》2002年第4期297-299,305,共4页Acta Universitatis Medicinalis Secondae Shanghai

基　　金：上海市技术发展基金项目计划 (98- 4 4 1 90 63)

摘　　要：目的探讨对高血压病患者脑腔隙性梗塞灶定量的可行性。　方法 1 利用脑腔隙性梗塞在摄片中的截面积作为衡量病灶体积大小的标准 ,建立病灶截面边界的手工粗定位和计算机软件精确定位相结合的定量分析方法。 2 30例确诊为腔隙性硬塞患者 ,经常规扫描法和重叠扫描法摄片后将图像输入定量分析软件包中测定病灶面积 ,检验该定量方法的可重复性。　结果同一病灶在 1周内两次摄片中所表现出的截面积接近 ( <5 %) ,摄片过程中头颅定位误差可予以忽略 ,手工粗定位的人为因素也可予以忽略 ( <5 %)。　结论脑腔隙性梗塞病灶定量是可行的 ,病灶在摄片中的截面积可以作为衡量病灶大小的可靠度量 ,截面积可用人机结合的方法进行精确测量 ,该法对进一步研究患者的病情发展、转归和药物疗效的定量评估有很大帮助。Objective To investigate the method to measure lacunar infarction quantitatively. Methods 1.Institute the technique for measuring lacunar infarction quantitatively roughly by manual localization and computer_aided accurately by localization. 2.Thirty hypertentive patients with lacunar infarction were committed to the quantitative analysis with regular and overlapped scan. Results The cross_section area of the lesion in shown MRI picture of same focus made twice in a week were approximately the same. Deviations of cranial localization and manual localization both can be ignored. Conclusion The cross_section area,being the reliable standard to represent the size of the lesion can be measured by the manual method combinaed with the computer method.This method of quantitative analysis can be used in further research study on lacunar infarction.

关 键 词：脑腔隙性梗塞 定量分析 MRI 

分 类 号：R743.3[医药卫生—神经病学与精神病学]