家兔循经组织温度变化与降钙素基因相关肽和血管紧张素Ⅱ含量的关系  

Relationship between the Change of Temperature and the Contents of CGRP and AⅡ in the Tissues along the Meridian in Rabbits

作　　者：马春红[1] 谭连红[1] 赵湘杰[1] 王淑友[1] 马惠敏[1] 张栋[1] 

机构地区：[1]中国中医研究院针灸研究所,北京100700

出　　处：《针刺研究》2002年第2期149-151,共3页Acupuncture Research

基　　金：国家九五攀登计划预选项目 (No.95 -预 - 19- 313);国家自然科学基金资助项目 (No .30 171176 )

摘　　要：目的 :探讨家兔循经组织温度变化与降钙素基因相关肽 (CGRP)和血管紧张素Ⅱ (AⅡ )含量的关系。方法 :运用红外热像技术 ,选取艾灸后家兔循经出现温度较高部位组织进行分析 ,用放射免疫方法测定外周组织CGRP及AⅡ含量变化。结果 :①循经组织温度较高部位CGRP含量与非高温区比较明显升高 (P <0 .0 0 1 ) ;②循经组织温度较高部位AⅡ含量与非高温区比较无明显改变 (P >0 .0 5)。结论 :艾灸后 。Objective: To observe the correlation between temperature changes and CGRP and AⅡ contents in the tissues along the meridians in the rabbit. Methods: Domestic rabbits were used in the present study. After removing the hair On the bilateral hind-limbs, the local body surface temperature was detected before and after moxibustion of 'Housanli' (for 15 min) using a infra-red thermography. The local skin, subcutaneous connective tissues and muscles where higher temperature band appeared along the meridian were taken for determining the contents of CGRP (calcitonin gene related peptide) and AⅡ (angiotensin Ⅱ) with radioimmunoassay. Results: The results showed that the content of CGRP in the higher temperature area tissues (14.9±9.11 pg/mg) was apparently higher than that (4.37±4.53 pg/mg)in the lower temperature area tissues (P<0.001); while no significant difference was found between higher and lower temperature area tissues in AⅡ contents (8.97±5.39 pg/mg vs 9.48±6.53 pg/mg,P>0.05). Conclusion: The results suggest that moxibustion induced increase of body surface temperature along the meridian is probably related to the release of CGRP in the peripheral tissue.

关 键 词：循经组织 温度 CGRP AⅡ 艾灸 

分 类 号：R224.1[医药卫生—中医基础理论]