t-PA治疗外伤性前房积血继发青光眼  

Treatment of secondary glaucoma following traumatic hyphema with t-PA.

作　　者：种平[1] 李润婷[1] 刘运甲 

机构地区：[1]河南省眼科研究所,450003 [2]伊川卫校附属医院

出　　处：《眼外伤职业眼病杂志》2002年第4期387-388,共2页Journal of Injuries and Occupational Diseases of the Eye with Ophthalmic Surgeries

摘　　要：目的　探讨组织型纤溶酶原激活剂 (tissueplasminogenactivator,t-PA)治疗外伤性前房积血继发青光眼的临床效果和安全性。方法　1 6例 (1 6眼 )保守治疗无效的眼挫伤引起的前房积血继发青光眼患者 ,平均眼压 43 1 8mmHg,于伤后 5～ 1 6d前房注入t -PA 1 0 μg。 结果　注药后 72h 1 6例前房积血全部吸收 ,48h眼压全部恢复正常。无并发症出现。结论　前房注射t-PA治疗外伤性前房积血继发青光眼是一安全。Objective To investigate the efficacy and safety of tissue plasminogen activatror(t-PA) in the treatment of secondary glaucoma following traumatic hyphema.Methods 16 cases(16 eyes) with uncontrolled glaucoma following traumatic hyphema were observed.The mean IOP was 43.18 mmHg.All cases received intracameral injection of t-PA 10μg at 5 to 16 days after injury.Results In all eyes,the hyphema resolved completely whin 24 to 72 hours and IOP returned to normal range witnin 24 to 48 hours after t-PA injection.Possible side effects were not observed.Conclusion Intracameral t-PA injection is safe and effective in the treatmeat of secondary glaucoma following traumatic hyphema.

关 键 词：T-PA 治疗 外伤性前房积血 继发性青光眼 眼球损伤 

分 类 号：R775.3[医药卫生—眼科]