应用免疫组化技术对NHL的免疫表型分型  

The application of imunohistochemistry for immunophenotying of Non-Hodgkin's Lymphoma

作　　者：马加东 陶淑芳 曹金龙[2] 陈利民[2] 范淼[2] 蔡清泉[2] 

机构地区：[1]上海市安亭医院病理科,上海201805 [2]解放军第四五五医院病理科

出　　处：《肿瘤》2002年第4期327-328,共2页Tumor

摘　　要：目的　应用免疫组化标记技术对NHL(Non Hodgkin’sLyphoma)免疫表型分型。方法　应用LCA、UCHL 1、L2 6、MAC、λ、K、EMA七个标记物对 38例NHL进行标记。结果　B细胞淋巴瘤 17例来源 (44 .7% ) ,T细胞淋巴瘤 16例 (42 .1% ) ,组织细胞来源淋巴瘤 3例 (7.9% ) ,B、T细胞来源淋巴瘤 2例 (5 .3% )。结论　免疫组化学标记技术对NHL诊断能提高诊断及分型水平。但对弥漫型NHL诊断中需与淋巴结反应性增生、神经内分泌癌 (小细胞型 )、未分化肉瘤、髓母细胞瘤、精原细胞瘤相鉴别。Objectives To investigate the use of immunohistochemistry ABC method for immunophenotying of NHL. Methods Mark 38 cases of Non Hodgkin's Lymphoma (NHL) with LCA, UCHL 1, L26, MAC,λ,K, EMA respectively. Results There are 17 cases of cell B originated lymphoma, (44.7%); 16 cases of cell T originated lymphoma(42.1%);3cases of tissue cell originated lymphoma(7.9%) and 2 cases of cell T.B originated lymphoma(5.3%).Conclusion The use of immunohistochemistry method is helpful both in the diagnosis of NHL and in typing.It can make diagnosis and typing more accurate .In case of diffuse type of NHL needs to be distinguished from lymphnode reactional hyperplasia neuroendocrine carcinoma (small cell type) , undifferentiated sarcoma and seminoma.

关 键 词：NHL 免疫组织化学 病理学 免疫表型分型 非何杰金氏淋巴瘤 

分 类 号：R733.1[医药卫生—肿瘤]