The effect of Daicong solution on the serum enzymes and LPO in aged rats dementia model  

作　　者：赵淑梅 张太国 岳启安 左凤英 李光宗 高敬宗 尤敏 管福来 

出　　处：《中国临床康复》2002年第15期2330-2331,共2页Chinese Journal of Clinical Rehabilitation

摘　　要：Objective To explore the effect of Daicong solu tion(DCS)on aged rats dementia model.Method The experiment used22-month old rats whose basal nuclei was destroyed by bilateral electrolytic method as model for aged rats dem entia.They were treated with DCS for a month.Then the level of superox ide dismutase(SOD),lipid peroxide(LPO),monoamine oxidase(MAO)and cholinesterase(CHE)in the serum was measured.Result Compared with the control,the activ ity of SOD increased markedly(P <0.01),the content of LOP and activity MAO and CHE were decreased(P <0.01).Conclusion DCS is effective in treating the aged dementia.Objective To explore the effect of Daicong solu tion(DCS)on aged rats dementia model.Method The experiment used22-month old rats whose basal nuclei was destroyed by bilateral electrolytic method as model for aged rats dem entia.They were treated with DCS for a month.Then the level of superox ide dismutase(SOD),lipid peroxide(LPO),monoamine oxidase(MAO)and cholinesterase(CHE)in the serum was measured.Result Compared with the control,the activ ity of SOD increased markedly(P <0.01),the content of LOP and activity MAO and CHE were decreased(P <0.01).Conclusion DCS is effective in treating the aged dementia.

关 键 词：呆聪液 老年性痴呆 血清酶 LPO 大鼠 作用机理 

分 类 号：R749.16[医药卫生—神经病学与精神病学] R965[医药卫生—临床医学]