肝癌介入化疗患者医院感染的临床特征和预防策略分析  

The clinical characteristics and preventive measures of nosocomial infection in patients with hepatocellular carcinoma after interventional chemotherapy

作　　者：董礼阳[1] 周为中[1] 余昶[1] 胡文豪[1] 黄士勇[1] 倪俊伟 张剑[1] 

机构地区：[1]温州医学院附属第一医院介入科,浙江温州325000

出　　处：《中国现代医学杂志》2014年第16期64-67,共4页China Journal of Modern Medicine

基　　金：温州市科技局项目(No:Y20110131)

摘　　要：目的回顾性分析该院的医院感染的临床特征，提出相对应的预防策略，为临床提出科学的指导意见以减少肝癌患者医院感染的发生。方法回顾性调查分析2010年1月-2013年10月在该院行肝癌介入化疗的患者1258例，调查表由该院自行统一制定，对肝癌介入化疗患者发生医院感染的临床资料进行统计分析，包含患者的感染部位、感染病原菌以及年龄等。结果医院感染发生率为5.33％；肝癌介入化疗患者以腹部和消化道、呼吸道的感染率比较高，分别为38．81％和29．84％；肝癌介入化疗患者中共检出病原菌37株，其中大肠埃希菌和铜绿假单胞菌的菌株比例最多，分别为18．92％和18．92％；肝癌介入化疗后感染患者各年龄组对比差异有显著性（P〈0．01）。结论在临床上，对于肝癌介入化疗患者需要重点保护易感人群，采取相应的有效预防策略。可以有效的减少医院感染的发生率。[ Objective ] To review the clinical features of the nosocomial infection in our hospital, and put forward corresponding preventive measures, and reduce the incidence of nosocomial infection in patients with liver cancer for clinical guidance. [Methods] Retrospective analysis was made of 1 258 cases of liver cancer chemotherapy in our hospital in 2010 January to 2013 October, unified registration form was to formulate, hepatocellular carcinomapatients with nosocomial infection were registered, statistics and analysis of infectionsite , the incidence of nosocomial infection in patients with pathogenic bacteria and age distribution data were made. [ Results ] The nosocomial infection rate was 5.33%; chemotherapy patients with abdominal and gastrointestinal and respiratory tract infection rate was higher, respectively 38.81%, 29.84%; 37 strains of pathogenic bacteria were detected in patients with hepatocellular carcinoma after interventional chemotherapy, the proportion of strains of Escherichia coli and Pseudomonas aeruginosa were the most, respectively 18.92%, 18.92%; each age group differences in patients with hepatoeellular carcinoma after interventional chemotherapy were statistical significance （P 〈0.01）. [ Conclusions ] In clinical, the protection of vulnerable populations need to focus on in the patients with hepatoeellular carcinoma after interventional chemotherapy, and effective preventive measures should be taken, which can effectively reduce the incidence of nosoeomial infection.

关 键 词：肝癌 介入化疗 医院感染 临床特症 预防策略 

分 类 号：R735.7[医药卫生—肿瘤]