非酒精性脂肪肝中医证候分布特点及与临床指标的相关性分析  

Correlation Analysis between Distribution Characteristics of TCM Syndromes and Clinical Index in Nonalcoholic Fatty Liver Disease

作　　者：陈阳[1,2] 冷雪[2] 杜莹[2] 韩永辉[2] 贾连群[2] 

机构地区：[1]沈阳市第六人民医院,辽宁沈阳110006 [2]辽宁中医药大学,辽宁沈阳110847

出　　处：《中华中医药学刊》2014年第7期1556-1558,共3页Chinese Archives of Traditional Chinese Medicine

基　　金：国家自然科学基金青年基金项目(81202834);沈阳市科学技术计划项目(F-12-277-1-49);辽宁省高等学校杰出青年学者成长计划资助项目(LJQ2011100)

摘　　要：目的：探讨非酒精性脂肪肝（NAFLD）中医证候分布特点及与B超、血清生化指标等的关系。方法：对诊断为NAFLD的235例患者进行中医辨证分型,并观察其证型与B超分度、血脂、肝功能酶学、血尿酸（UA）、血糖（Glu）等的关系。结果：各证型发病率由高到低分别为脾虚湿滞型、湿热困脾型、肝郁脾虚型,各证型出现的高峰期主要集中在41～60岁;轻度NAFLD多集中于肝郁脾虚型,中度多集中于脾虚湿滞型,重度多为湿热困脾型;肝郁脾虚型谷酰转肽酶（GGT）水平较其他两型低,湿热困脾型甘油三酯（TG）水平较其他两型高。结论：NAFLD患者客观化指标与中医辨证分型具有一定的内在关系。Objective：It is to investigate the distribution of TCM syndromes of nonalcoholic fatty liver disease（NAFLD） and its correlations with B-ultrasonic and serum biochemical indices.Methods：The syndromes of 235NAFLD patients were categorized and its correlations with B-ultrasonic grade,blood lipids,hepato-enzymes,blood uric acid（UA） and serum glucose（Glu） were analyzed.Results：The incidence of Chinese Medical Pattern from high to low were dampness stagnancy due to spleen deficiency,damp-heat besieging in the spleen,liver depression and spleen deficiency and each pattern in the rush hour mainly concentrated in 41 ～ 60 years old.Mild NAFLD more focused on the liver depression and spleen deficiency.The moderate NAFLD more focused on the dampness stagnancy due to spleen deficiency and severe NAFLD was damp-heat besieging in the spleen.The level of gamma-glutamyl transpeptidasethe（GGT） of liver depression and spleen deficiency was lower than that of the other two.The triglyceride（TG） levels of damp-heat besieging in the spleen were higher than that of the other two.Conclusion：There are same internal relationships between the objective indices of NAFLD and TCM syndrome differentiation.

关 键 词：非酒精性脂肪肝 中医证候 客观化指标 

分 类 号：R575[医药卫生—消化系统]