胚胎停育史患者再次妊娠干预措施的临床研究  

Clinical Study on Intervention Measures of Re-pregnancy in People with Embryo Damage History

作　　者：王瑜 韩玉芬 王志勇 李文媛 

机构地区：[1]河南省濮阳市妇幼保健院妇产科,河南濮阳457000

出　　处：《中国医药指南》2014年第19期56-57,共2页Guide of China Medicine

摘　　要：目的探讨采取干预措施对胚胎停育史患者再次妊娠成功率的影响。方法排除染色体异常和其他已知的可能影响胚胎发育的因素,筛查出510例有胚胎停育史患者,据患者意愿将其分不选择前期治疗,要求妊娠后直接保胎者(A组,n=169)和选择妊娠前后综合治疗者(n=341),后者根据干预措施不同分为阿司匹林组(B组,n=106),淋巴细胞主动免疫治疗组(C组,n=110)和阿司匹林和淋巴细胞主动免疫相结合治疗组(D组,n=125),观察各组再次妊娠成功率。结果 B、C、D组再次妊娠成功率均高于A组,D组高于B组和C组,差异均具有显著性意义(均P<0.05);B组和C组再次妊娠的成功率无统计学意义(P>0.05)。结论采取干预措施可有效提高胚胎停育史患者再次妊娠成功率。Objective To explore the effects after being treated with intervention measures on re-pregnancy success rate of people with embryo damage history. Methods Excluded chromosome abnormality and other known factors which may have effect on embryo development, 510 patients with embryo damage history were divided into two instances according to their willingness. One instance was group A （n=169）, without previous treatment, received only fetus protection after pregnancy, the other one （n=341） was received combined treatments before and after pregnancy, and it was divided into three groups according to intervention measures（group B, group C and group D） again. Aspirin group （group B, n=106）, lymphocyte initiative immtmotherapy group （group C, n=t 10） and comprehensive treatment group （group D, n=125）, then the re-pregnancy success rate was compared in every group. Results The success rate of re-pregnancy in group B,C and D was higher than that in group A, the success rate of re-pregnancy in group D was higher than that in group B and group C, and there were significance in statistics（P〈0.05）.But there were no significant difference in group B and group C（P〉0.05）.Couelusion Taking intervention measures can effectively increase the successful rate of re-pregnancy in people with embryo damage history.

关 键 词：胚胎停育 染色体异常 妊娠 

分 类 号：R71[医药卫生—妇产科学]