幽门螺杆菌感染状态与缺铁性贫血发生关系Meta分析  

A Meta-analysis on relationship between Helicobacter pylori infection and iron-deficiency anemia

作　　者：季娜[1] 李昊[1] 梁国威[1] 

机构地区：[1]航天中心医院检验科,北京100049

出　　处：《检验医学与临床》2014年第13期1771-1772,1775,共3页Laboratory Medicine and Clinic

摘　　要：目的探讨中国儿童幽门螺杆菌感染与缺铁性贫血（IDA）的关系。方法计算机检索中国知网、万方数据库、pubmed数据库,收集2004年1月1日至2013年11月1日儿童幽门螺杆菌感染与IDA关系的病例对照研究,用Meta分析估计其综合优势比（OR）值和95%可信区间（CI）。结果共有5个研究纳入Meta分析。两组采用固定效应模型的Meta分析,合并OR=3.17,95%CI为3.17（2.41～4.17）。结论幽门螺杆菌感染与IDA具有较高的相关性,当儿童IDA治疗效果欠佳时,可以考虑幽门螺杆菌感染,应及时进行抗感染治疗。Objective To explore the association between Helicobacter pylori infection and iron-deficiency anemia（IDA）among the children in China.Methods CNKI,Wanfang and pubmed database were retrieved.Research of the relationship between helicobacter pylori infection and IDA among the children in China,based on case-control study and published from Jan.1of 2004to Nov.1of 2013,were collected.Then the literatures were analyzed by using Meta analysis to evaluate the comprehensive ORvalue and 95%CI.Results A total of five studies were included into Meta analysis.Fixed effect models were used in two groups,and the comprehensive ORvalue and 95%CI were 3.17and 2.41-4.17,respectively.Conclusion Helicobacter pylori infection might be correlated with IDA.Thus,when children with IDA are undergoing ineffective treatment,Helicobacter pylori infection might be considered and timely treated.

关 键 词：幽门螺杆菌 缺铁性贫血 META分析 

分 类 号：R573[医药卫生—消化系统]