胸腺瘤Masaoka分期及WHO分型与重症肌无力关系的临床意义  

Clinical significance of relationship between the myasthenia gravis and the WHO histological type ＆ Masaoka clinical stages of thymoma

作　　者：朱豫[1] 朱健[1] 刘勇[1] 朱水波[1] 晏明[1] 周孜孜[1] 

机构地区：[1]广州军区武汉总医院心胸外科,武汉430070

出　　处：《国际外科学杂志》2014年第6期394-396,共3页International Journal of Surgery

摘　　要：目的 探讨胸腺瘤Masaoka分期及WHO分型与重症肌无力关系的临床意义.方法 回顾性分析2004年12月-2009年9月胸腺瘤切除标本及完整病例81例,运用统计学软件分析胸腺瘤Masaoka分期及WHO分型与重症肌无力的关系.结果 胸腺瘤Masaoka临床不同分期之间合并重症肌无力的发病率差异有统计学意义（P＜0.05）.胸腺瘤WHO组织学不同分型之间合并重症肌无力的发病率差异有统计学意义（P＜0.05）.胸腺瘤Masaoka临床分期与WHO组织学分型之间的关系差异有统计学意义（P＜0.05,κ =0.580,C=0.503）.结论 胸腺瘤Masaoka临床分期与合并重症肌无力有一定的关系,胸腺瘤WHO组织学分型与合并重症肌无力也有一定的关系,同时WHO分型在一定程度上反映了Masaoka临床分期,因而在一定程度上可以作为评价患者预后的重要指标之一.Objective To investigate the clinical significance of relationship between the myasthenia gravis and WHO histological types ＆ Masaoka clinical stage of thymoma.Methods Retrospective analysis of resection specimen in thymoma and complete medical records in 81 cases from December 2004 to September 2009,using the analysis of statistical software between myasthenia gravis and both thymoma Masaoka clinical stages ＆ the WHO histological types.Results The difference of merger with MG of thymoma Masaoka among different clinical stages was statistically significant （P ＜ 0.05）.The difference of merger with MG Thymoma WHO among different histological types was statistically significant （P ＜ 0.05）.The difference of thymoma Masaoka between the WHO histological type and Masaoka clinical stages was statistically significant （P ＜ 0.05,kappa =0.580,C =0.503）.Conclusions There are some relationships between thymoma Masaoka clinical stages and MG,so had some relationships between thymoma WHO histological types and MG.At the same time,the thymoma WHO histological types reflects the Masaoka clinical stages in a certain extent.This relationship would be used as one of the important indicators to evaluate the prognosis of patients at some extent.

关 键 词：胸腺瘤 WHO分型 Masaoka分期 重症肌无力 相关性 预后 

分 类 号：R736.3[医药卫生—肿瘤]