腹腔镜下射频消融治疗特殊部位肝癌35例疗效观察  

Clinical observation on therapeutic efficiency of laporascopic radiofrequency ablation for liver cancer with specific locations

作　　者：张辉[1] 徐新保[1] 刘承利[1] 何晓军[1] 张洪义[1] 

机构地区：[1]空军总医院肝胆科,北京100142

出　　处：《西部医学》2014年第7期872-873,875,共3页Medical Journal of West China

摘　　要：目的探讨特殊部位的肝癌经腹腔镜下射频消融治疗的安全性及疗效。方法分析医院近10年对35例特殊部位肝癌患者行腹腔镜下射频消融术的临床资料,根据术后复查增强CT、MRI,观察并发症的发生率及治疗效果。结果所有病例均顺利完成腹腔镜下射频消融治疗,未出现胆瘘、胃、肠道瘘及膈肌损伤、大出血、肝功能衰竭等严重并发症。术后1个月复查增强CT、MRI、甲胎蛋白,肿瘤完全消融患者32例（91.4%）,随访6～48个月,平均22个月,其1、2、3年生存率分别为73.7%、61.6%、53.6%。结论特殊部位肝癌患者行腹腔镜下射频消融治疗,可减少并发症的发生和提高射频消融的效果,同时也为合并肝硬化、肝功能较差不能耐受手术切除的患者提供了一种有效可行的治疗方式。Objective To evaluate the safety and efficiency of laporascopic radiofrequency ablation（LRFA）for patients with specially located liver cancers.Methods 35 patients diagnosed as liver cancer with specific locations were retrospectively studied.After LRFA,surgical complications and therapeutic efficiency were evaluated through contrast-enhanced CT and MRI.Results All the 35 patients successfully went through LRFA therapy.None of the severe postoperative complications such as biliary fistula,gastrointestinal fistula,diaphragmatic injury,massive hemorrhage and hepatic failure was observed.Contrast CT and MRI studies combined with AFP test were taken one month after LRFA showed tumor disappeared in 95.1% of the patients.With a median follow-up of twenty-two months（ranged from six to fortyeight months）,the overall survival was 73.7%,61.6% and 53.6% for the 1-,2-and 3-year after LRFA respectively.Conclusion For patients with specially located liver cancers,LRFA is an feasible and effective therapeutic approach to improve outcomes and reduce therapy-related complications.Furthermore,it also provides an additional therapeutic choice for patients who are intolerant for surgical resections because of cirrhosis and impaired liver function.

关 键 词：肝癌 肝硬化 射频消融 腹腔镜 

分 类 号：R735.7[医药卫生—肿瘤]