基于库尔特计数器原理的纳通道热气泡检测系统  

Detection System of Thermal Bubble in a Nanochannel Based on Coulter Counter Principle

作　　者：陈敏[1] 蒋大伟[1] 姜昆鹏 陈冬冬[1] 

机构地区：[1]江苏大学机械工程学院,镇江212013

出　　处：《纳米技术与精密工程》2014年第4期275-280,共6页Nanotechnology and Precision Engineering

基　　金：国家自然科学基金资助项目(51206064);江苏省高校自然科学基金资助项目(12KJB470003);江苏大学人才启动基金资助项目(12JDG051)

摘　　要：本文提出并实现了一种基于库尔特计数器原理的纳通道热气泡检测技术.利用微纳加工技术,设计、制作了可以有效检测纳米级通道中的热气泡特性的实验器件,搭建了检测平台,实际考察了截面尺寸为100 nm×100nm的纳通道中的热气泡成核行为.实验结果表明,随着纳通道中溶液温度的逐渐增加,流经纳通道的电流逐渐增大,而后呈下降趋势,再经过一段时增时减的复杂变化后,电流信号最终消失.实验结果间接表明,纳通道中产生了阻碍电流的热气泡,热气泡体积的增大与减小对应通道电流的减小与增加,经过一段复杂的体积变化后,热气泡最终完全阻塞了纳通道.可见,基于库尔特计数器原理的纳通道热气泡检测器件可以有效用于纳通道中热气泡复杂行为的研究.Nano-scale thermal bubble nucleation was investigated based on the principle of Coulter counter in this paper. With micro-nano fabrication technology, a device was designed and fabricated, and adetection platform was set up to investigate the thermal bubble nucleation of aqueous solution confined ina nanochannel with a cross section size of about 100 nm × 100 nm. Results show that with the increase ofthe temperature of the solution confined in the nanochannel, the current through the channel increasesfirstly and then decreases, until vanishes after a fluctuating period. It is found that the thermal bubblesgenerated hinder the current from flowing through the nanochannel. In addition, the shrinking or expan-ding of thermal bubbles＇ volume correspond to the increase or decrease of current. Finally, the thermalbubbles block the nanochannel entirely. Experiment results indicate that our device can be applied to investigate the complex behaviors of thermal bubble produced in aqueous solution confined in nanochannelseffectively.

关 键 词：纳通道 热气泡 库尔特计数器 微纳加工 

分 类 号：TH724[机械工程—仪器科学与技术] TP274[机械工程—精密仪器及机械]