善宁治疗65例肝硬化合并急性上消化道大出血的疗效及预后分析  

Octreotide in treatment of 65 cases of liver cirrhosis curative effect and prognosis of acute upper digestive tract bleeding with

作　　者：黄美勇 

机构地区：[1]广西巴马瑶族自治县人民医院内三科,广西巴马547500

出　　处：《吉林医学》2014年第20期4394-4396,共3页Jilin Medical Journal

摘　　要：目的:观察善宁治疗65例肝硬化合并急性上消化道大出血的疗效及预后。方法:收集65例肝硬化合并急性上消化道大出血的患者,分为治疗组与对照组,分别使用善宁和垂体后叶素,收集其治疗前后的临床数据,并随防6个月,分析其治疗有效率、输血量、止血时间、住院时间、出院后再次出血次数、再次住院次数的差异。结果:①治疗组与对照组相比,临床总有效率差异有统计学意义(P<0.05),输血量、止血时间、住院时间差异有统计学意义(P<0.01)。②治疗组与对照组相比较,出院后6个月内再次上消化道出血次数、再次入院次数差异有统计学意义(P<0.05)。结论:善宁可以有效治疗肝硬化合并急性上消化道大出血,减少输血量,缩短止血时间、住院时间,并减少远期上消化道再血及再入院。Objective To observe the clinical effect of sandostatin on upper gastrointrstinal hemorrhage with cirrhosis.Methods 65 definite patients patients were randomly divided into two groups.The treatment group were injected sandostatin and the control group were injected pituitrin.Results：①The gross treatment outcome,average of haemostasis time,the volume of blood transfusion of the treatment group are significantly superior to the control group（P〈0.05）.There were significant differents between treatment group and control group on the average of haemostasis time,the volume of blood transfusion,Hospitalized time of the treatment group（P〈0.01）.②Follow-up fo six months,the number of Rebleeding and readmission of the treatment group were significantly superior to the control group（P〈0.05）.Conclusion The treatment of sandostatin on upper gastrointestinal hemorrhage with cirrhosis has a better clinical therapeutic effect,and can shorten the haemostasis time and decreased the volume of blood transfusion,rebleeding time and readmission time.

关 键 词：善宁 肝硬化 上消化道大出血 疗效 预后 

分 类 号：R575.2[医药卫生—消化系统] R573.2[医药卫生—内科学]