苏木醇提取物对实验性重症肌无力小鼠巨噬细胞的影响  

The Effect of Ethanol Extracts of Caesalpinia Sappan L.on Macrophage Function in EAMG Rats

作　　者：赖成虹[1] 余秀[1] 

机构地区：[1]内江市第一人民医院神经内科,四川内江641000

出　　处：《中国医药指南》2014年第21期3-3,共1页Guide of China Medicine

基　　金：四川省中医药管理局(2004A37);四川省泸州市科学技术局资助项目((2004)60号-11)

摘　　要：目的观察EAMG小鼠巨噬细胞(Mφ)的功能。方法复制EAMG小鼠模型,注入苏木醇提取物治疗,检测其Mφ的功能。结果EAMG对照组小鼠Mφ的吞噬功能明显增强,EAMG治疗组明显降低(P<0.05)。结论苏木具有下调EAMG小鼠Mφ功能从而发挥治疗作用。Objective To explore the macrophage cell（Mφ）competence in experimental autoimmune myasthenia gravis（EAMG）rats. Methods The EAMG model in rats was induced, the ethanol extracts of Caesalpinia Sappan L were given to the EAMG treatment group, the Mφcompetence was test. Reslut The Mφcompetence of the EAMG treat group were much lower than that of the EAMG control group（P〈0.05）. Conclusion The Caesalpinia Sappan L is able to suppress the Mφcompetence in EAMG.

关 键 词：苏木 实验性重症肌无力 巨噬细胞 

分 类 号：R746.1[医药卫生—神经病学与精神病学]