80例肝癌患者的病因及临床特征分析  

Analysis of Clinical Characteristics and Etiology on Liver Cancer Patients:An Analysis of 80 Cases

作　　者：张英辉[1] 闫伟 

机构地区：[1]北京崇文光明医院内科(北京军区空军司令部门诊部内科),北京100061 [2]清华大学第一附属医院消化内科,北京100016

出　　处：《中国医药指南》2014年第21期55-56,共2页Guide of China Medicine

摘　　要：目的：探讨肝癌的主要发病原因及其临床特征。方法采用回顾性分析的方法对我院80例肝癌患者的性别、年龄、首发症状、主要病因以及病毒标志物等进行研究。结果80例患者中，男女患病比例为2.2∶1，患者年龄主要集中在60~70岁，首发症状主要以胁痛、食欲下降为主，主要发病因素多为乙肝病毒感染（67.5%），其次为脂肪肝（18.8%）。其中由乙肝病毒感染引起的肝癌患者中，HBeAg阳性者占59.3%，HBeAg阴性者占40.7%，HBV DNA载量≥104拷贝/毫升占77.8%。结论男性、年龄＞55周岁的患者是肝癌的多发人群，乙肝病毒感染是其主要致病因素，HBV DNA载量多在104拷贝/毫升以上，此外，患者多伴有阵发性胁痛及食欲下降。Objective To explore the main etiology and clinical features of hepatocellular carcinoma（HCC）. Methods A retrospective analysis which contains the patient＆#39;s gender, age, symptoms, the main etiology, HBV markers and other clinical date were being studied among 80 cases of HCC patients in our hospital. Results Among the 80 cases of HCC patients, the ratio between men and women was 2.2∶1, and their age was mainly concentrated in 60 to 70 years old. Hypochondriac pain and loss of appetite were the main clinical features, and fatter liver was the main etiology（18.8%）which is followed by HBV infection（67.5%）. Among HCC patients caused HBV infection, HBeAg （＋） was accounting59.3%, while HBeAg （-） was accounting 40.7%, and HBV DNA loads 104 copies/mL was accounting 77.8%. Conclusion Male and older than 55 ages were the frequent occurrence cause of HCC and HBV infection was the main factor, and the HBV DNA loads were mainly more than 104 copies/mL. in addition,patients suffered from HCC were always combined paroxysmal hypochondriac pain and loss of appetite.

关 键 词：肝癌 病因 临床特征 

分 类 号：R735.7[医药卫生—肿瘤]