清洁腮腺手术围术期抗菌药物对术后组织愈合的影响  

Effect of perioperative use of antibiotics on healing in clean parotidectomy

作　　者：张瑞[1] 杨建荣[1] 

机构地区：[1]南京医科大学口腔医学研究所,江苏省210029

出　　处：《江苏医药》2014年第13期1514-1516,共3页Jiangsu Medical Journal

基　　金：江苏高校优势学科建设工程资助项目(2011137)

摘　　要：目的探讨清洁腮腺手术围术期抗菌药物对术后组织愈合的影响。方法回顾性分析260例腮腺肿块手术治疗患者的临床资料。260例分为A组(使用抗菌药物,119例)和B组(未使用抗菌药物,141例)。A、B组又分为有感染风险因素的A1组(37例)、B1组(42例)和无感染风险因素的A2组(82例)、B2组(99例)。结果 A、B组在术后72h内体温升高、切口裂开、线头反应、涎瘘和手术部位感染方面比较均无统计学差异(P>0.05)。A1组切口裂开发生率高于A2组(16.2%vs.2.4%)(P<0.05);B1组切口裂开发生率高于B2组(19.0%vs.3.0%)(P<0.01)。结论清洁腮腺手术可以不使用抗菌药物预防术后感染,也并不会影响术后的组织愈合。Objective To analyze the effect of perioperative use of antibiotics on the healing in clean parotidectomy.Methods Data of 260patients underwent clean parotidectomy for parotid mass were retrospectively analyzed,who were divided into two groups of A（with perioperative use of antibiotics,119cases）and B（without perioperative use of antibiotics,141cases）.According to the risk factors for infection,group A was subdivided into groups of A1（with risk factors,37cases）and A2（without risk factors,82cases）and group B was subdivided into groups of B1（with risk factors,42cases）and B2（without risk factors,99cases）.The postoperative fever in 72hafter surgery,wound dehiscence,thread reaction,salivary fistula and wound infection were compared.Results There were no significant differences in the postoperative fever in 72hafter surgery,thread reaction,salivary fistula and wound infection between groups of A and B.The incidence rate of wound dehiscence was higher in group A1than that in group A2（16.2% vs.2.4%）（P〈0.05）.So did that was higher in group B1than that in group B2（19.0% vs.3.0%）（P〈0.01）.Conclusion Clean parotidectomy may not use any antibiotics to prevent postoperative infection,which does not affect wound healing.

关 键 词：腮腺手术 抗菌药物 

分 类 号：R782[医药卫生—口腔医学]