80例微栓子阳性脑梗死患者危险因素分析  

Analysis of the risk factors of 80 cases of cerebral infarction with microembolus

作　　者：吴海波[1] 张云云[1] 王晔[1] 龙燮[1] 甄晓敏[1] 

机构地区：[1]上海中医药大学附属岳阳中西医结合医院,上海200437

出　　处：《热带医学杂志》2014年第6期774-776,共3页Journal of Tropical Medicine

基　　金：上海市教委优秀青年教师资助课题(SZY10082)

摘　　要：目的探讨微栓子(MES)阳性脑梗死患者的危险因素及病因分型。方法回顾性分析80例MES监测阳性的脑梗死患者和同期88例MES监测阴性的脑梗死患者的临床资料,比较两组患者脑梗死危险因素及病因的差异。结果微栓子阳性与心房颤动、高血脂、高同型半胱胺酸血症、颈动脉不稳定斑块显著相关(P<0.05);改良TOAST分型显示,微栓子阳性脑梗死患者心源性栓塞及动脉粥样硬化血栓形成型比例明显高于微栓子阴性脑梗死患者。结论房颤、颈动脉不稳定斑块、异常的血流及血液成分是微栓子形成的主要因素,易发生或易再发脑梗死。Objective To explore the causes and classification of microembolus in cerebral infarction. Methods 80 cases of cerebral infarction with microembolus and 88 cases of cerebral infraction without microembolus were analyzed retrospectively. And 88 cerebral infarction patients without micrombolus. Results There were significant correlations between atrial fibrillation, dyslipidemia, hyperhomocysteinemia, carotid artery plaques and microembolus （P〈0.05）. The ratio of cardiogenic embolism （CE） and atherosclerosis thrombus formation （AT） with microembolus was significantly higher than that without microembolus in patients with cerebral infarction. Conclusion Atrial fibrillation, carotid artery plaques, blood and blood components,is the main factor to the forming of microembolus, and the recurrent of cerebral infarction.

关 键 词：脑梗死 微栓子 病因 分型 危险因素 

分 类 号：R743.9[医药卫生—神经病学与精神病学]