某石化企业作业工人脂肪肝危险因素研究  

Study on risk factors of fatty liver among employees in a petrochemical enterprise

作　　者：王卉[1] 薄亚莉 张倩[1] 陈会祥[1] 周君[1] 李敏嫣[1] 

机构地区：[1]天津渤海化工集团有限责任公司劳动卫生研究所,天津300051

出　　处：《工业卫生与职业病》2014年第4期270-274,共5页Industrial Health and Occupational Diseases

摘　　要：目的了解石化工人脂肪肝发病现状及危险因素。方法以某石化企业炼油部1494名作业工人为调查对象进行脂肪肝影响因素流行病学现况调查，同时收集2007--2012年职业健康检查资料进行比较。结果2012年度检出脂肪肝421例，检出率为28．0％；男性为33．2％，女性为13．3％，男性约为女性的2．5倍。脂肪肝的总检出率有随年龄增加而增高趋势，30-39、40-49、≥50岁组与20-29岁组比较，差异均有统计学意义（P〈0．01）。调查对象脂肪肝检出率2012年比2007年明显增加，差异有统计学意义（P〈0．01）。血脂检测结果异常者及高血糖、高纤维蛋白原、高血压、心电图异常者的脂肪肝检出率均较高，差异有统计学意义（P〈0．01或0．05）；脂肪肝组丙氨酸转氨酶和尿酸升高者检出均高于无脂肪肝组，差异有统计学意义（P〈0．01）。非条件logistic回归分析，调查对象体质量指数、甘油三酯、性别为脂肪肝危险因素。结论石化工人脂肪肝的检出率较高，脂肪肝的发生与多种因素有关，建议采取控制体重及饮酒等措施，对脂肪肝发生进行干预。Objective To understand the status and its risk factors of fatty liver among petrochemical workers. Methods Epidemiological investigation was conducted on influencing factors of fatty liver among 1494 workers in a refining department of a petrochemical enterprise. Meanwhile, occupational health examina- tion data from 2007 to 2012 were collected for comparison. Results In 2012, 421 cases of fatty liver were de- tected, and the detection rate was 28.0%. The rate in male was 33.2-, which was about 2.5 times com- pared to that of female （13.3-）. Total detection rate of fatty liver increased with the age. The 30-39, 40- 49 and -50 age groups were compared with 20 - 29 age group respectively, and the statistical significant difference was found（P〈0. 01）. The detection rate in 2012 was significantly higher than that in 2007, and the difference was statistical significance （P〈0.01）. The higher detection rates of fattey liver were found in the workers with lipid abnormality, hyperglycemia, high fibrinogen, hypertension and abnormal ECG, and the difference was statistical significance （P 〈 0.01 or 0.05）. There were more detecting cases of elevated ALT and uric acid in fatty liver group compared to those in non-fatty liver group （P〈0.01）. The non-conditional lo- gistic regression analysis showed that body mass index, triglyceride and gender were risk factors of fatty liv- er. Conclusions It was suggested that the fatty liver should be intervened by weight and drinking control.

关 键 词：脂肪肝 危险因素 石化工人 

分 类 号：R575.502[医药卫生—消化系统]