68例腔隙性脑梗死MRI表现与血脂变化的相关性研究  

The correlation of magnetic resonance imaging and lipid levels in 68 cases of lacunar infarction

作　　者：田力[1] 赵一蓉[1] 刘翠芳[1] 

机构地区：[1]重庆市中医院放射科,400000

出　　处：《重庆医学》2014年第20期2563-2564,2568,共3页Chongqing medicine

摘　　要：目的探讨腔隙性脑梗死(LI)的MRI表现与血脂变化的相关性。方法回顾性分析68例LI患者的MRI表现及其血脂水平,选取62例同期住院就诊的非心脑血管疾病患者为对照组,应用多元Logistic回归分析LI的MRI表现与血脂变化的相关关系。结果 LI患者MRI共检出299个腔隙性病灶,其中梗死病灶位于左侧大脑半球58个(19.40%),右侧大脑半球26个(8.70%),双侧基底节区73个(24.41%),丘脑27个(9.03%),侧脑室旁放射冠54个(18.06%),脑干39个(13.04%),小脑22个(7.36%)。LI患者的TC、TG、LDL-C和Ox-LDL水平显著增高(P<0.05),而HDL-C的水平明显低于对照组(P<0.05)。多元Logistic回归分析显示TC、TG、LDL-C、HDL-C和Ox-LDL对LI的相对危险度分别为1.56、1.27、1.39、1.46和1.44。结论 LI患者的MRI表现与血脂水平有一定程度的相关性,血脂水平升高可能是LI的重要危险因素。Objective To explore relationship between magnetic resonance imaging （MRI） performance and lipid levels in pa-tients with lacunar infarction （LI） .Methods 68 patients with LI were retrospectively analyzed ,62 cases patients without heart ce-rebrovascular disease in the same period were choosen as control group ,the multivariate logistic regression was used to analyze the relationship between MRI performance ,the changed level of lipid .Results A total of 299 lacunar lesions were detected by MRI ,in which there were 58（19 .40% ）in the left cerebral hemisphere ,26（8 .70% ） in the right hemisphere ,73（24 .41% ） in the bilateral basal ganglia ,27 （9 .03% ） in thalamus ,54 （18 .06% ） in the lateral ventricles corona radiata ,39 （13 .04% ） in brainstem ,and 22 （7 .36% ） in cerebellum .TC ,TG ,LDL-C and Ox-LDL levels in LI patients were significantly higher than the controls （P〈0 .05） , while HDL-C levels were significantly lower than the controls （P〈0 .05） .Multivariate Logistic regression analysis showed that relative risk of TC ,TG ,LDL-C ,HDL-C and Ox-LDL to LI were 1 .56 ,1 .27 ,1 .39 ,1 .46 and 1 .44 .Conclusion The MRI manifestations and lipid levels of LI have a certain degree of correlation ,and elevated blood lipid levels may be important risk factors for LI .

关 键 词：磁共振成像 血脂 危险因素 腔隙性脑梗死 

分 类 号：R743.33[医药卫生—神经病学与精神病学] R445.2[医药卫生—临床医学]