睾丸间质细胞瘤2例报告并文献复习  

Report of two cases of testicular leydig cell tumor and literature review

作　　者：杨宪法[1] 赵耀瑞[1] 王勇[1] 杨福江[1] 郜海涛[1] 齐灿[1] 孙光[1] 徐勇[1] 

机构地区：[1]天津医科大学第二医院泌尿外科天津泌尿外科研究所,300211

出　　处：《现代泌尿生殖肿瘤杂志》2014年第3期161-163,共3页Journal of Contemporary Urologic and Reproductive Oncology

摘　　要：目的探讨睾丸间质细胞瘤的临床病理特点,进而提高睾丸间质细胞瘤的诊治水平。方法回顾性分析2例睾丸间质细胞瘤的临床病理资料并复习相关文献。结果 1例术中快速冷冻切片病理诊断为睾丸间质细胞瘤,行根治性睾丸切除术,1例直接行根治性睾丸切除术,术后病理均诊断为睾丸间质细胞瘤,其中1例精索残端及周围脂肪组织可见肿瘤细胞,精索静脉可见肿瘤浸润。术后分别随访24和6个月,未见复发或转移。结论睾丸间质细胞瘤临床罕见,术前诊断较为困难,确诊仍依赖组织病理学检查,外科手术是睾丸间质细胞瘤唯一有效的治疗方法。Objective To investigate the clinical-pathological characteristics of the testicular leydig cell tumor （LCT）, to improve diagnosis and treatment level. Methods 2 cases of LCT were retrospectively analyzed, and the related literatures were reviewed. Results Case one was diagnosed by intraoperative frozen section pathological examination, and was treated with radical orchiectomy; case two was treated with radicalorchiectomy directly, and definitive pathological examination con- firmed LCT, tumor cells were visible at the spermatic cord stump and fat tissue around. Tumor infiltration was visible in spermatic vein. The two patients were followed up 24, 6 months respectively. No local recurrences or metastases were found. Conclusions LCT of the testis is a rare tumor lacking of a typical clinical manifestation, and preoperative diagnosis is difficult. The diagnosis depends on histopathological examination. Surgical treatment is the only effective way for LCT.

关 键 词：睾丸肿瘤 间质细胞瘤 诊断 治疗 

分 类 号：R737.21[医药卫生—肿瘤]