黄浦江流域典型药物和个人护理品的含量及分布特征  

Concentrations and distribution of selected pharmaceuticals and personal care products in Huangpu River

作　　者：王丹[1] 隋倩[1] 吕树光[1] 赵文涛[2] 邱兆富[1] 余刚 

机构地区：[1]华东理工大学,国家环境保护化工过程环境风险评价与控制重点实验室,上海200237 [2]同济大学环境科学与工程学院,污染控制与资源化研究国家重点实验室,上海200092 [3]清华-威立雅先进环境技术联合研究中心,北京100084

出　　处：《中国环境科学》2014年第7期1897-1904,共8页China Environmental Science

基　　金：国家自然科学基金(51208199);中国博士后科学基金特别资助项目(2013T60429);国家环境保护环境微生物利用与安全控制重点实验室开放基金(MARC2011D032;MARC2011D044);环境模拟与污染控制国家重点联合实验室开放基金(12K02ESPCT);中央高校基本科研业务费专项资金

摘　　要：采用固相萃取-高效液相色谱/串联质谱法(SPE-HPLC-MS/MS)分析上海市黄浦江流域7种典型药物和个人护理品(PPCPs)的含量水平.结果表明,所建立的分析方法具备良好的回收率(87%~107%)、相对标准偏差(<14%)及方法定量限(0.1~1.1ng/L),满足水体中微量污染物的检测要求.应用该方法检测得到,上海市黄浦江流域水体中目标PPCPs的含量在<LOQ^824ng/L范围内,总体浓度水平较低,符合我国药物消费特点.从污染物的空间分布特征看,下游污染比上游严重,支流污染程度大于干流.The concentrations of 7selected pharmaceuticals and personal care products （PPCPs） in the Huangpu River were determined by solid phase extraction and high liquid chromatography-electrospray tandem mass spectrometry （SPE-HPLC-MS/MS）. The results showed that the developed analytical method obtained good recoveries （87-107%）, relative standard deviation （〈14%） and limit of quantification （0.1-1.1ng/L）, satisfying the requirement to detect micropollutants in the surface water. By applying the method in Huangpu River, we found that compared to other reported studies, the contamination levels of target PPCPs were low in Huangpu River, with the concentrations varying from ＆lt;LOQ to 824ng/L, which were consistent with their consumptions in China. Higher total concentrations were observed in downstream and tributaries sampling sites than in upstream and stream sites.

关 键 词：药物和个人护理品 高效液相色谱 串联质谱法 黄浦江 浓度水平 

分 类 号：X171[环境科学与工程—环境科学]