儿童霍奇金淋巴瘤治疗相关性白血病1例并文献复习  

Child-Hodgkin's lymphoma with acute myeloid leukemia subtype M2:a case report and literature review

作　　者：于倩倩[1] 李红玲[2] 张旭霞[2] 

机构地区：[1]宁夏医科大学血液内科,银川750001 [2]甘肃省人民医院肿瘤内科

出　　处：《临床血液学杂志》2014年第4期607-609,共3页Journal of Clinical Hematology

基　　金：国家自然科学基金资助课题(No:30960438)

摘　　要：随着化疗和放疗在霍奇金淋巴瘤（HL）治疗中的广泛应用，治疗相关性白血病（TRL）的发病率逐渐增高。儿童急性髓系白血病（AML）M2型在临床上较少见，继发于HL者更为少见。现报告我院1例患儿的临床资料，并进行文献复习。A child suffered from Hodgkin lymphoma（HL）with acute myeloid leukemia subtype M2（AMLM2）was reported.Karyotype analysis was 46,XX,（20）;HLA-DR,CD13,CD33,CD34,CD38,CD117and CD123were expressed through flow cytometry.Excluding the preceding acute lymphoblastic leukemia,the child was diagnosed as therapy-related leukemia（AML-M2）.After the chemotherapy of one cycle IDA and one cycle FLAG,the bone marrow was complete remission.TRL is a complication following exposure to cytotoxic agents and radiotherapy in the treatment of primary malignancies,with poor prognosis and long-term survival rates.

关 键 词：白血病 髓系 急性 治疗相关性白血病 淋巴瘤 

分 类 号：R733.71[医药卫生—肿瘤]