基于数据挖掘的国医大师颜正华临床用药规律研究  

Rules of Property of Drugs Used by State Medical Master Yan Zhenghua Based on Data Mining

作　　者：吴嘉瑞[1] 郭位先[1] 张晓朦[1] 张冰[1] 

机构地区：[1]北京中医药大学,北京100102

出　　处：《中国中医药信息杂志》2014年第8期16-18,共3页Chinese Journal of Information on Traditional Chinese Medicine

基　　金：国家科技支撑计划(2007BAI10B01);北京市中医药科技发展基金(JJ-2010-70);北京市自然科学基金(7112075);北京中医药大学科研创新团队项目(2011-CXTD-14)

摘　　要：目的探讨国医大师颜正华临床用药规律。方法收集颜正华教授处方,基于"中医传承辅助平台系统(V2.0.1)"构建处方数据库,采用软件方剂分析等模块,分析处方用药基本特点。结果就四气而言,温性药物频次最多(7998次),其次为凉性(7866次)、平性(6763次)、寒性(3942次)、热性(95次);就五味而言,苦味药物频次最多(15 260次),其次为甘味(10 810次)、辛味(10 453次)、酸味(2794次)、咸味(1651次)、淡味(1203次)、涩味(186次);就归经而言,肝经频次最多(14 237次),其次为肺经(10 452次)、脾经(10 061次)等。结论颜正华教授处方用药以温、凉药为主,甘、辛味药居多,药物归经以肝、肺、脾经为主,与颜正华用药平和轻灵特点相吻合。Objective To analyze the rules of property of the drugs used by State Medical Master Yan Zhenghua in clinical.Methods The prescriptions used by Pro. Yan were collected to build a database, which was based on traditional Chinese medicine inheritance assistant software. After analyzed by the software, such as using the module to analyze the prescriptions, the medication characters of the prescriptions can be got from the database.Results Drugs of warm nature were used with the highest frequency 7998 times, followed by the cool 7866 times, leveling 6763 times, cold 3942 times, and hot 95 times. From the property of five flavors, the most used flavor of drugs was bitter 15260 times, followed by sweet 10810 times, pungent 10453 times, sour 2794 times, salty 1651 times, mild 1203 times, and astringency 186 times. In the frequency of the channel tropism involved, the highest is of liver channel 14237 times, followed by lung 10452 times and spleen 10061 times.Conclusion Pro. Yan was accustomed to using the drugs that were of warm and cool natures, and sweet and pungent flavors, and also the drugs that have action on the collateral channels of liver, lung and spleen, which were the same as the experience from Pro. Yan.

关 键 词：名医经验 颜正华 中药 四气五味 归经 数据挖掘 

分 类 号：R2-05[医药卫生—中医学] R285.6