恶性胰岛细胞瘤术后肝转移介入治疗临床分析:附8例报道并文献复习  

Effect of interventional therapy on malignant islet cell tumor of liver metastasis after surgery:A report of eight cases and review of literature

作　　者：商春雨[1] 常继红[1] 张立明[1] 

机构地区：[1]中国医科大学四平医院,吉林四平136000

出　　处：《现代肿瘤医学》2014年第7期1636-1637,共2页Journal of Modern Oncology

摘　　要：目的:探讨肝动脉化疗栓塞术治疗恶性胰岛细胞瘤外科术后肝转移患者的临床疗效。方法:回顾性分析在我科行介入治疗的8例恶性胰岛细胞瘤术后肝转移患者。原发灶位于胰颈部1例,胰体尾部7例。7例为肝脏多发转移,1例为肝内单一病灶。所有患者均接受1-6次肝动脉化疗栓塞术。结果:8例患者均获得随访,随访0.5-8年。其中部分缓解(PR)6例,稳定(SD)2例,进展(PD)0例。目前仍生存6例,最长已生存8年,死亡2例。1例伴有低血糖患者空腹血糖恢复正常水平,所有患者均出现程度不等的术后反应,但未出现严重并发症。结论:恶性胰岛细胞瘤外科术后肝转移患者行肝动脉化疗栓塞术安全,疗效确切。Objective：To explore the clinical therapeutic effect of transcatheter arterial chemoembolization in the treatment of liver metastasis of malignant islet cell tumor after surgery. Methods ：To retrospectively analyze the effect of interventional therapy for eight cases of liver metastasis of malignant islet cell tumor after surgery. Primary tumor lo- cated in the neck of pancreas body in one case and tail of pancrea body in seven cases. Seven cases of liver metasta- sis,one case was single lesion in the liver. All patients were treated with 1 - 6 times of transcatheter hepatic arterial chemoembolization. Results： Eight patients were followed up for 0.5 - 8 years, PR in six cases, SD in two cases, PD zero. There were six patients still survived, the longest survival was eight years, two cases dead. The fasting blood glu- cose returned to normal levels in one case. All patients had different degree postoperative reaction. There were no seri- ous complications. Conclusion：Hepatic arterial chemoembolization for malignant islet cell tumor after surgery in pa- tients with liver metastases is safe and effective.

关 键 词：恶性胰岛细胞瘤 肝转移 肝动脉化疗栓塞术 

分 类 号：R735.9[医药卫生—肿瘤]