子宫肌瘤对子宫内膜容受性的影响  

Effect of Leiomyoma of Uterus on Endometrial Receptivity

作　　者：孙瑜[1] 朱依敏[1] 

机构地区：[1]浙江大学医学院附属妇产科医院生殖内分泌科,杭州310006

出　　处：《生殖与避孕》2014年第7期576-579,共4页Reproduction and Contraception

摘　　要：子宫内膜容受性是影响胚胎着床的重要因素之一,子宫肌瘤是生育期女性最常见的良性肿瘤,对子宫内膜容受性的影响深受关注,其对子宫内膜容受性的影响不是局限于肌瘤表面而是遍布整个宫腔。除了引起宫腔形态改变外,子宫肌瘤可通过局部血供受损、子宫内膜免疫状态失衡、细胞因子分泌异常、着床相关因子改变等损害子宫内膜容受性;但子宫肌瘤是否影响子宫内膜着床尚未达成一致意见。Endometrial receptivity plays a key role in the establishment of successful pregnancies. Leiomyomas of uterus are the most common solid pelvic tumors in women. Several studies have shown an unfavorable effect of fibroids on endometrial receptivity. Its effect on endometrial receptivity is not confined to the myoma surface but throughout the whole of the uterine cavity. In addition to cause the change of uterine cavity shape, uterine fibroids may affect the endometrial receptivity by damaging the local blood, endometrial immune imbalance, abnormal secretion of cytokines, implantation related factors. But whether the leiomyomas affect endometrial implantation have not yet reached consensus.

关 键 词：子宫肌瘤 影响 子宫内膜容受性 

分 类 号：R737.33[医药卫生—肿瘤]