中老年人动脉粥样硬化性脑卒中血清CRP与血脂水平关系分析  

Analysis on the Relationship of the Serum CRP and Blood Lipid Levels of the Elderly Patients with the Atherosclerotic Stroke

作　　者：赵娜[1] 郭刚[1] 张瑞[1] 王红莉[1] 冯亚莉[1] 

机构地区：[1]延安大学附属医院检验科,陕西延安716000

出　　处：《现代生物医学进展》2014年第25期4899-4902,共4页Progress in Modern Biomedicine

摘　　要：目的:探讨中老年人动脉粥样硬化性脑卒中血清CRP与血脂水平关系。方法:2011年3月至2013年2月选择我院收治的中老年人动脉粥样硬化性脑卒中120例作为观察组,同期门诊选择健康中老年人120例作为对照组,两组都进行血清CRP与血脂的测定并进行相关分析。结果:多因素logistic回归分析结果显示TC、CRP、LDL-C与HDL-C是导致中老年人动脉粥样硬化性脑卒中发病的独立危险因素(P<0.05)。观察组的血清CRP含量明显高于对照组,TC、TG与LDL-C含量明显高于对照组,而HDL-C含量明显低于对照组,对比差异都有统计学意义(P<0.05)。血清CRP≥3 mg/L患者(n=80)的TC、TG与LDL-C含量也明显高于血清CRP<3 mg/L患者(n=40),对比差异也有统计学意义(P<0.05)。结论:中老年人动脉粥样硬化性脑卒中患者表现为血清CRP、TG、LDL-C和TC的升高,它们也是脑卒中的独立危险因素,同时CRP水平可以预测相关血脂指标的变化。Objective： To investigate the relationship of the CRP in serum and the blood lipid levels for elderly patients with the atherosclerotic stroke. Methods： 120 elderly patients with the atherosclerotic stroke who were treated in our hospital from March 2011 to February 2013 were admitted as the observation group, and another 120 healthy elderly people were chosen to be the control group. The serum CRP and the lipid of the two groups were detected and correlation analysis. Results： Multivariate logistic regression analysis showed that TC, CRP, LDL-C and HDL-C were the main risk factors for the atherosclerotic stroke （P〈0.05）. The serum CRP, TC, TG and LDL-C levels of the observation group were significantly higher, and the HDL-C level were significantly lower than those of the patients in the control group （P〈0.05）. The TC, TG and LDL-C levels of the serum CRP≥3 mg/L in patients（n=80） were also significantly higher than those whose serum CRP〈3 mg/L （n=40） （P〈0.05）. Conclusion： Atherosclerotic stroke in the elderly patients showed serum CRP, TC, TG, LDL-C were elevated, and they were also the independent risk factor for stroke, while CRP levels can predict the changes in lipid -related indicators.

关 键 词：血脂 CRP 中老年人 动脉粥样硬化性脑卒 

分 类 号：R743[医药卫生—神经病学与精神病学]