脂肪肝患者的肝功酶谱结果分析  

Analysis of the results of hepatic enzyme in patients with fatty live

作　　者：何静[1] 杨玉娟[1] 曾伟宏[1] 迟琼[1] 

机构地区：[1]广州医科大学附属第四医院检验科,广州511447

出　　处：《广州医药》2014年第4期53-55,共3页Guangzhou Medical Journal

摘　　要：目的通过脂肪肝患者的肝功酶谱结果分析,判断其在酒精性脂肪肝(AFLD)和非酒精性脂肪肝(NAFLD)诊断及鉴别中的意义。方法通过62例AFLD患者及108例NAFLD患者与100例非脂肪肝健康人的肝功酶谱结果,进行对比分析。结果 AFLD组和NAFLD组的丙氨酸氨基转移酶(ALT)、天门冬氨酸氨基转移酶(AST)、γ-谷氨酰转肽酶(GGT)、胆碱酯酶(CHE)的结果高于健康对照组(P<0.01),其中CHE敏感性最高。碱性磷酸酶(ALP)结果在三组间的差异无统计学意义(P>0.05)。AFLD组的GGT、AST结果和异常率高于NAFLD组,尤其GGT(P<0.01)。结论通过肝功酶谱结果分析,对帮助诊断及鉴别AFLD和NAFLD有一定的价值。Objective To investigate the value of diagnostic by analysing the changes of hepatic enzyme activity in alcoholic fatty liver（AFLD） and nonalcoholic fatty liver（NAFLD）.Methods The results of hepatic enzyme in 62 patients with AFLD and 108 patients with NAFLD and 100 healthy people were analyzed and compared.Results The activity of alanine aminotransferase（ALT）,aspartate aminotransferase（AST）,gamma glutamyl transpeptidase（GGT） and cholinesterase（CHE） in AFLD group and NAFLD group were significantly higher than those in healthy controls（P〈0.01）,where CHE is the most sensitive.Alkaline phosphatase（ALP） showed no significant differences（P〉0.05）.The Abnormality rate of GGT and AST in AFLD group were higher than NAFLD group,where GGT is the most sensitive（P〈0.01）.Conclusion Analysing hepatic enzyme has certain value for diagnosis and differential diagnosis of AFLD and NAFLD.

关 键 词：酒精性脂肪肝 非酒精性脂肪肝 肝脏酶学 

分 类 号：R575.5[医药卫生—消化系统]