脑型Wilson病患者智力水平及智力结构的研究  

Study on intelligence level and intelligence structure in brain type patients with Wilson's disease

作　　者：李波[1] 王共强[1] 韩咏竹[1] 韩永升[1] 马心峰 

机构地区：[1]安徽中医药大学神经病学研究所附属医院,合肥230061

出　　处：《安徽医学》2014年第4期420-422,共3页Anhui Medical Journal

基　　金：安徽省卫生厅科研基金项目(2012zy65)

摘　　要：目的通过神经心理学测验评估脑型Wilson病(Wilson's disease,WD)患者晶体智力和流体智力水平,探讨其智力结构变化的特点及相关因素。方法选取32例脑型WD患者为研究对象,采用韦氏智力量表、瑞文标准推理测验(R'SPM)进行晶体智力和流体智力测评,运用SPSS 11.5软件分析患者的晶体智力、流体智力变化及相关因素。结果 43.75%脑型WD患者晶体智力水平下降,78.13%脑型WD患者流体智力水平下降,瑞文标准推理测验智商(RWIQ)得分低于韦氏智力测定全量表智商(FIQ)得分(P<0.05);韦氏智力测定言语量表智商(VIQ)、韦氏智力测定操作量表智商(PIQ)与FIQ呈正相关(P<0.05),瑞文标准推理测验E分测验(RWE)、性别与RWIQ呈正相关(P<0.05),FIQ与RWIQ无相关性(P>0.05)。结论脑型WD患者的智力结构存在不均衡受损,流体智力水平下降较晶体智力水平更为明显。流体智力和晶体智力不可相互替代。Objective Through conducting neuropsychological test to evaluate crystallized intelligence and fluid intelligence of brain type patients with Wilson's disease ( WD) ,to analyze the characteristics of intelligence structure changing and other related factors .Methods Wechsler intelligence test and Raven's standard progressive matrices ( R'SPM) were conducted among 32 brain type WD patients ,in order to assess crystallized intelligence and fluid intelligence .The diversities of patients crystallized intelligence , fluid intelligence and other related factors were analysed by using SPSS 11.5 software.Results 43.75%brain type WD patients showed a decrease in crystallized intelligence while 78.13%patients showed fluid intelligence drop .Moreover,Raven's standard progressive matrices intelligence quotient (RWIQ) ranking was significantly less than full measuring scale intelligence quotient (FIQ) (P<0.05),verbal intelligence quotient (VIQ) and performance intelligence quotient (PIQ )appeared significantly positive correlation (P<0.05) with FIQ.In addition,RWE,gender showed significantly positive correlation(P<0.05) with RWIQ;however,FIQ did not show any relation with RWIQ(P>0.05).Conclusion Brain type WD pa-tients'intelligence structure has unbalanced damage ,and fluid intelligence decreases more obviously than crystallized intelligence .The fluid in-telligence and crystallized intelligence cannot replace with each other .

关 键 词：WILSON病 肝豆状核变性 晶体智力 流体智力 相关因素 

分 类 号：R742.4[医药卫生—神经病学与精神病学]