形态学结合3T功能成像组合诊断乳腺肿瘤的价值  

Value of morphology combined with functional imaging at 3T in diagnosis of breast tumors

作　　者：王俊[1] 卢环[1] 吴婷[1] 

机构地区：[1]赣南医学院第一附属医院影像科,江西省赣州市341000

出　　处：《实用医学杂志》2014年第15期2411-2414,共4页The Journal of Practical Medicine

基　　金：江西省卫生厅课题(编号:20093087)

摘　　要：目的:探讨形态学基础上磁共振功能成像(氢质子波谱、弥散、MR动态增强)在乳腺肿瘤诊断中的优化组合及价值。方法:收集2009-2013年来我院经临床及病理诊断为乳腺肿瘤的患者140例,其中恶性肿瘤63例,良性肿瘤77例,且同时行基础扫描、1H-MRS、DWI及动态增强检查的患者资料,将所得图像信息分析,并与病理结果比较,得出基础图像上波谱、弥散、动态增强两两组合信息对乳腺癌诊断的敏感性、特异性、准确性。结果:所有病例均病理证实。基础图上DWI、动态增强组合检查诊断乳腺癌的敏感性89.8%,特异性90.1%,准确性90.0%;MRS、动态组合检查诊断乳腺癌的敏感性为77.9%,特异性77.3%,准确性79.3%;DWI、MRS联合检查诊断乳腺癌的敏感性76.3%,特异性77.8%,准确性77.1%;3种组合检查诊断乳腺癌结果比较,χ2=9.057,P=0.011,差异有显著性。结论:基础图像上DWI与动态增强组合对乳腺肿瘤诊断的敏感性、特异性及准确性最高,可以作为乳腺肿瘤功能成像最佳组合。Objective To investigate the optimal combination and the value of functional magnetic resonance imaging in the diagnosis of breast tumors. Methods One hundred and forty patients who had been clinically and pathologically diagnosed as breast tumors in our hospital during the period of 2009 to 2013 were collected. 63 of whom had breast cancer and 77 had benign tumor. All the patients received 1H-MRS, DWI and dynamic enhanced MRI at the same time. The obtained images were analyzed and then compared with the pathological findings. The accuracy, sensitivity, and specificity of MRS combined with DWI or dynamic enhanced MRI, or DwI combined with enhanced MRI in the diagnosis of breast cancer were obtained. Results All the diagnosis were pathologically confirmed. The accuracy, sensitivity, and specificity were 89.8%, 90.1%, and 90.0% for DWI combined with dynamic contrast-enhanced MRI; 77.9%, 77.3% and 79.3% for MRS in combination with enhanced MRI; and 76.3%, 77.8% and 77.1% for DWI combined with MRS. There were significant differences among the three kinds of combination detection in diagnosis of breast cancer, x2 = 9.057, P = 0.011. Conclusions The sensitivity, specificity and accuracy is the highest in DWI combined with dynamic enhanced MRI in the diagnosis of breast tumor, which can be used as the best combination imaging for breast tumor.

关 键 词：乳腺肿瘤 磁共振波谱 弥散 动态增强 

分 类 号：R737.9[医药卫生—肿瘤]