儿童急性小脑共济失调23例临床分析  

Clinical analysis of 23 cases of children with acute cerebellar ataxia

作　　者：陈凤民[1] 

机构地区：[1]河南省人民医院儿科,郑州450003

出　　处：《中国实用神经疾病杂志》2014年第15期23-24,共2页Chinese Journal of Practical Nervous Diseases

摘　　要：目的探讨儿童急性小脑共济失调的临床、实验室及影像学检查特征、治疗和预后。方法回顾分析我院收治的23例儿童急性小脑共济失调患者的临床资料,对病因、临床表现、脑脊液检查、头部CT和MRI结果及治疗进行分析。结果23例急性小脑共济失调患者中前驱感染占82.6%,脑脊液白细胞轻度增多占30.4%,头CT检查无异常,MRI检查异常率17.4%,激素治疗3d症状减轻6例,10d明显好转23例,20d全部症状体征消失,2个月后随访无复发。结论儿童急性小脑共济失调病因以感染多见,结合临床表现进行脑脊液、头CT和MRI检查是早期正确诊断的关键,及时应用激素治疗预后良好。Objective To explore the clinical ,laboratory and imaging testing characteristics ,treatment as well as progno-sis of children with acute cerebellar ataxia .Methods Clinical data of 23 cases treated in our hospital were analyzed ,an analysis of the pathogenic factors ,their clinical manifestations ,cerebrospinal fluid examination ,results of the brain CT and MRI and their treatment effectiveness was made .Results Among the 23 cases ,children with the prodromal infection accounted for 82 . 6% and those with slight increase of white corpuscles in cerebrospinal fluid accounted for 30 .4% .CT test on head showed no abnormality while the abnormal rate in MRI test amounted to 17 .4% .With the treatment of hormone ,symptoms of 6 cases be-came less obvious with 6 days＆#39;treatment and 23 cases turned evidently well within 10 days＆#39;treatment ;all the pathological symp-toms disappeared with 20 days＆#39;treatment .In addition ,there was no relapse of the disease in the two months＆#39;follow-up .Conclu-sion A majority of cases of children with acute cerebellar ataxia are caused by infection .The key to a correct early-stage diag-nosis lies in the check of cerebrospinal fluid ,brain CT and MRI ,in combination with the individual clinical manifestation ,it is advisable to apply hormone in time for treatment and they may gain good prognosis .

关 键 词：儿童 小脑共济失调 

分 类 号：R742.82[医药卫生—神经病学与精神病学]