急性脑梗死患者血清P-、L-选择素及CRP的表达与神经功能缺损的关系  

Study on the Relationship between Serum P-,L-Selectin and CRP Expression and Neurological Deficit of Acute Cerebral Infarction Patients

作　　者：周义杰[1] 王红[1] 韦华军[1] 马继红[1] 王培力[1] 王树青[1] 

机构地区：[1]广西桂林市中医医院,广西桂林541002

出　　处：《云南中医中药杂志》2014年第7期21-22,共2页Yunnan Journal of Traditional Chinese Medicine and Materia Medica

基　　金：广西科技厅科技攻关项目;桂科攻(NO:0993003D-12)

摘　　要：目的探讨急性脑梗死患者血P-、L-选择素及CRP表达与神经功能缺损的关系。方法将160例急性脑梗死患者按神经功能缺损程度分为轻中重3组,分别测定脑梗死患者的P-、L-选择素及CRP水平,分别进行组间比较。结果急性脑梗死患者神经功能缺损的严重程度与血P-、L-选择素及CRP表达呈正相关,神经功能缺损严重的患者血P-、L-选择素及CRP表达水平较高(P<0.01/0.05)。结论急性脑梗死患者血P-、L-选择素及CRP的联合检测可以作为判断脑梗死患者神经功能缺损严重程度的指标之一。Objective： To study the relationship between serum P-,L-selectin and CRP expression and neurological deficit of acute cerebral infarction patients. Methods： 160 patients were divided into heavy,moderate and light groups by neurological deficit and their P-,L- selectin and CRP levels were measured and compared. Results： The degree of the neurological deficits showed a positive correlation with the serum P-,L- selectin and CRP expression,and the patients with severe neurological deficits had high levels of serum P-,L- selectin and CRP expression（P ＆lt;0. 01 /0. 05）. Conclusion： The joint detection of P-,L- selectin and CRP of the acute cerebral infarction patients may be a marker to judge the neurological defect severity of the patients.

关 键 词：P-、L-选择素 CRP 脑梗死 神经功能缺损 

分 类 号：R743.33[医药卫生—神经病学与精神病学]