腮腺巨大多形性腺瘤1例并文献复习  

Giant pleomorphic adenoma of the parotid gland:one case report and review of the literature

作　　者：赵世杰[1,2] 赵峰[1] 苏纪平[1] 

机构地区：[1]广西医科大学第一附属医院耳鼻咽喉-头颈外科,南宁530021 [2]广西天等县人民医院五官科,广西天等532800

出　　处：《临床耳鼻咽喉头颈外科杂志》2014年第14期1066-1069,共4页Journal of Clinical Otorhinolaryngology Head And Neck Surgery

摘　　要：目的:回顾性分析腮腺巨大多形性腺瘤(GPA)的临床特征、病理机制、诊断与治疗方法。方法:报告1例GPA的诊治经过,并复习国内外相关文献报道,分析GPA的临床特征、病理机制、影像学表现、病理组织学、诊断与治疗方法。结果:GPA多见于高龄患者,病程多长达10年以上,有恶变可能;CT扫描显示肿块密度不均,呈不同程度强化,边界清晰。病理学检查见肿瘤组织由腺上皮细胞、肌上皮细胞和黏液成分组成。结论:GPA是少见病,常表现为耳下侧颈部无痛性,缓慢生长的巨大肿块。其发病与人为因素有关。其诊断不难,依靠病史、查体及影像学检查即可作出诊断。保留面神经功能的肿瘤全切除术是治疗的有效方式。ObjectiveTo investigate the cause, genetics, clinical features, pathological mechanism, diagonosisand treatment of the Giant pleomorphic adenoma of the parotid gland（GPA）. Method：A case of GPA was reportedand relevant literatures were reviewed. Result： GPAs were more commonly found in elderly patients, duration ofmore than 10 years, with a possible malignant degeneration. CT scan shows uneven density,different degrees ofenhancement and clear boundary. Pathological examination shows that the composition of tumor tissue are epitheli-al cells, myoepithelial cells and mucus. Conclusion： GPA is an uncommon disease and is associated with human fac-tors. The diagnosis of GPA is oriented by medical history, physical examination and imaging tests. The total re-section of the tumor and preservation of the facial nerve is an effective way for the treatment of GPA.

关 键 词：多形性腺瘤 腮腺肿瘤 面神经 手术 恶变 

分 类 号：R739.6[医药卫生—肿瘤]