宫颈微偏腺癌的诊治进展  

Minimal deviation adenocarcinoma of the uterine cervix- Progress of the clinical diagnosis and treatment

作　　者：洪开[1] 姜继勇[2,3] 

机构地区：[1]大连医科大学研究生院,辽宁大连116044 [2]大连医科大学附属大连市妇产医院 [3]大连市妇幼保健院妇科病房,辽宁大连116033

出　　处：《大连医科大学学报》2014年第3期287-290,共4页Journal of Dalian Medical University

摘　　要：宫颈微偏腺癌(Minimal deviation adenocarcinoma of the uterine cervix,MDA)是一种极为特殊的宫颈腺癌类型,最常见的临床症状为阴道排液,最常见的体征为宫颈肥大。因癌变病灶位置较深,组织学特殊,临床诊断较困难,常规检查易漏诊、误诊,病理组织学检查是最终确诊依据,联合免疫组化检测可提高诊断准确性。明确诊断后应尽早采用根治性手术治疗,术后辅助放、化疗。由于MDA具有浸润深、转移快的恶性生物学行为,而且发病早期诊断困难,对放、化疗不敏感,总体预后较差。Minimal deviation adenocarcinoma of the uterine cervix （ MDA） is a very special type of cervical adenocarcino-ma.Vaginal drainage is the most common clinical symptom and cervical hypertrophy is the most common sign .Due to the deep location of the cancerous lesion , special histologic findings , and difficulty in clinical diagnosis , MDA is easily missed and misdiagnosed by regular check -up.Histologic examination provides the final diagnosis with improved diagnostic accu-racy by immunohistochemical stains .A radical hysterectomy should be adopted as soon as possible once the diagnosis is es -tablished, combined by post-surgical adjuvant chemotherapy and radiation therapy .Nevertheless, the overall prognosis of MDA remains poor due to the malignant biological behavior of the tumor with deep invasion and rapid metastasis , difficulty in early diagnosis , and resistance to chemo -radiation therapy .

关 键 词：宫颈 微偏腺癌 恶性腺瘤 诊断 

分 类 号：R737.33[医药卫生—肿瘤]