经皮肝穿刺胆道腔内射频消融联合支架植入治疗恶性梗阻性黄疸(附2例报告)  

Percutaneous endobiliary radiofrequency ablation combined with biliary stenting for the treatment of malignant obstructive jaundice: report of two cases

作　　者：鲁东[1] 吕维富[1] 肖景坤[1] 周春泽[1] 

机构地区：[1]合肥安徽省立医院影像科,230001

出　　处：《介入放射学杂志》2014年第7期593-596,共4页Journal of Interventional Radiology

摘　　要：目的探讨经皮肝穿刺胆道腔内射频消融(RFA)联合支架植入治疗恶性梗阻性黄疸的安全性和疗效。方法对2例恶性梗阻性黄疸患者在行经皮肝穿刺胆道引流术后,行经皮胆道腔内RFA联合支架植入术,观察并发症、疗效及术后50 d支架通畅情况。结果 2例患者均成功接受手术治疗,技术成功率100%。均行分段RFA,术后血清总胆红素水平显著下降。均无胆道出血、胆管穿孔、胆漏等严重并发症发生,随访50 d月支架通畅。结论经皮肝穿刺胆道腔内射频消融联合支架植入作为恶性梗阻性黄疸介入治疗的新方法,是安全及有效的,但仍需有效的随机对照试验来证实。Objective To evaluate the safety and efficacy of percutaneous endobiliary radiofrequency ablation combined with biliary stenting in treating malignant obstructive jaundice. Methods Percutaneous endobiliary radiofrequency ablation combined with biliary stenting was carried out in 2 patients with malignant obstructive jaundice after they received percutaneous transhepatic biliary drainage. The curative effect, complications and stent patency at 50 days after the treatment were recorded. The results were analyzed. Results Successful endobiliary radiofrequency ablation and intraluminal stent implantation was accomplished in both patients, with a technical success rate of 100%. Segmental radiofrequency ablation procedure was employed. After the treatment the serum total bilirubin level was significantly decreased. No bile duct bleeding, perforation of bile duct, bile leakage or other serious complications occurred. The stent remained unobstructed during the follow - up period of 50 days. Conclusion As a new treatment for malignant obstructive jaundice, percutaneous endobiliary radiofrequency ablation combined with biliary stenting is clinically safe and effective, although its long - term efficacy needs to be further proved with randomized controlled trials.

关 键 词：恶性梗阻性黄疸 射频消融术 支架 介入放射学 

分 类 号：R735.7[医药卫生—肿瘤]