不同金属胆道支架对恶性梗阻性黄疸疗效比较  

Biliary stenting for the treatment of malignant obstructive jaundice: comparison study of different metallic stents

作　　者：路绪龙 白旭明[1] 程龙[1] 顾星石[1] 靳勇[1] 

机构地区：[1]江苏苏州苏州大学附属第二医院介入科,215004

出　　处：《介入放射学杂志》2014年第7期606-610,共5页Journal of Interventional Radiology

摘　　要：目的评估两类常用金属支架治疗不同位置的恶性胆道梗阻支架通畅率及患者生存率。方法对126例因恶性胆道梗阻接受经皮经胆道金属支架植入治疗的患者进行回顾性分析,共植入金属胆道支架167枚,其中70例患者植入网状编织型支架92枚,56例患者植入激光雕刻型支架75枚。术后随访并比较患者支架通畅时间及生存时间。结果支架植入成功率为100%(126/126),网状型与激光型中位通畅时间分别为182 d、196 d,术后患者的中位生存时间分别为179 d、186 d。两组患者术后通畅率及生存率进行对比分析差异均无统计学意义(P>0.05)。结论网状型与激光型支架在治疗恶性胆道梗阻效果上基本等效。在一定程度上前者可起到替代作用。Objective To evaluate the patency rate of two types of metallic biliary stent in treating malignant biliary stenosis, and to discuss the patient’s survival rate. Methods A total of 126 patients with malignant biliary stenosis were treated with percutaneous implantation of biliary stent. The clinical data were retrospectively analyzed. A total of 167 metallic biliary stents were used in 126 patients. Ninety - two metal stents of mesh type were employed in 70 cases, while 75 metal stents of laser engraving type were adopted in 56 cases. After the treatment all patients were followed up, and the stent patency time as well as the median survival time was determined. The results were analyzed and compared between the two types of stents. Results Technical success rate was 100% （126/126）. The median patency rate time of mesh type and laser type was 182 days and 196 days respectively, the patient’s median survival time of mesh type group and laser type group was 179 days and 186 days respectively. No statistically significant differences in the stent patency time and in the median survival time existed between the two groups （P 〉 0.05）. Conclusion In treating malignant biliary obstruction with stenting, the mesh type stent and the laser type stent have quite same therapeutic effect. Therefore, in clinical practice the two types of stent can be replaced with each other to a certain degree.

关 键 词：金属胆道支架 恶性梗阻性黄疸 通畅率 生存率 

分 类 号：R735.7[医药卫生—肿瘤]