竖直矫治对倾倒磨牙龈沟液中白细胞介素-1β,白细胞介素-6及白细胞介素-8水平的影响  

Effect of Molar Erection on the Levels of Interleukin-1,Interleukin-6 and Interleukin-8 in Gingival Crevicular Fluic

作　　者：张立亚[1] 王梦婷[2] 江勋 张敏[2] 

机构地区：[1]昆明医科大学附属口腔医院,云南昆明650031 [2]云南省第一人民医院,昆明理工大学附属医院口腔矫形科,云南昆明650032 [3]昆明云天口腔,云南昆明650031

出　　处：《昆明医科大学学报》2014年第7期12-16,共5页Journal of Kunming Medical University

基　　金：云南省应用基础研究基金资助项目(2009ZC162M)

摘　　要：目的对磨牙竖直前后龈沟液中白细胞介素-1β(Interleukin-1β),白细胞介素-6及白细胞介素-8水平的测定,探讨正畸竖直磨牙对牙周组织的影响.方法选择近中倾倒的磨牙30颗,通过正畸治疗将其竖直.分别在治疗前,治疗后1周,完全竖直后及治疗完成后1周对竖直磨牙进行临床检查,检测软垢指数(Bleedingindex),牙龈出血指数(Gingivalindex),龈沟探诊深度(Gingivalcrevice depth),并进行龈沟内取样,检测龈沟液中IL-1β,IL-6及IL-8水平.结果与治疗前相比,近中倾倒的磨牙在治疗结束1周后,各项临床指标及白细胞介素水平与治疗前相比差异有统计学意义(P<0.05).同时,完全竖直后与粘结矫治器1周时相比,各项临床指标及白细胞介素水平差异有统计学意义(P<0.05).结论竖直近中倾倒的磨牙有利于其牙周组织的健康.Objective To investigate the effect of molar erection on periodontal tissue by measuring the levels of interlerkin-1β , IL-6 and IL-8 in gingival crevicular fluid （GCF） during the orthodontic treatment. Methods 30 slanted molars were erected. During the treatment, the clinical parameters including bleeding index （BI） , gingival index （GI） and gingival crevice depth （GCD） were detected at the point of pre-erecting, 1-week after beginning treatment, finishing treatment and 1-week after finishing treatment. GCF was also collected from buccal and lingual of medial site and distal site at each time point and the level of IL-1β , IL-6 and IL-8 were detected. Results At the point of the finishing treatment, GI, GCD and all GCF indexes showed significant differences as compared to 1-week after beginning treatment. And at the point of 1-week after finishing treatment, all indexes showed significant differences as compared to pre-erecting. Conclusion Erecting the molar has good effect on the periodontal tissue.

关 键 词：磨牙 竖直 白细胞介素 

分 类 号：R781.4[医药卫生—口腔医学]