河北丰宁地区妇女人乳头瘤病毒感染及疫苗认知状况调查  

An investigation of HPV prevalence among women living in Fengning of Hebei Province and their awareness toward knowledge of HPV and HPV vaccine

作　　者：张晓晓[1,2] 赵超[1] 崔淑慧[1] 赵昀[1] 毕显清 赵丽君[1] 魏丽惠[1] 

机构地区：[1]北京大学人民医院妇产科,100044 [2]北京大学深圳医院 [3]河北省丰宁满族自治县中医院妇产科

出　　处：《中国妇产科临床杂志》2014年第4期318-321,共4页Chinese Journal of Clinical Obstetrics and Gynecology

基　　金：北京群众宫颈癌筛查认知度的建立及科普推广活动(Z121110001912169);子宫颈癌及癌前病变防治策略的建立和推广(Z121100005512002);国家自然科学青年基金(81001157)

摘　　要：目的调查河北省丰宁满族自治县妇女人乳头瘤病毒（HPV）感染及对宫颈癌、HPV和HPV疫苗的认知情况,并探讨宣教对其认知度的影响。方法对河北丰宁地区717例18~45岁妇女进行HPV相关知识的问卷调查及宣教,对其中647例妇女留取宫颈脱落细胞进行高危型HPV DNA检测。结果高危型HPV总检出率为16.07%（104/647）;14.78%（106/717）的妇女曾听说过HPV,HPV知晓率与年龄、婚姻情况、户口类型及教育程度有关（P〈0.05）;84.38%（605/717）的妇女从未行宫颈癌筛查,在112例行宫颈癌筛查的妇女中,末次筛查为巴氏涂片、宫颈液基细胞学和HPV检测者分别为16.07%（18/112）、39.29%（44/112）和8.04%（9/112）;宣教后HPV知晓率显著提高（P〈0.05）;15.76%（113/717）的妇女既往听说过HPV疫苗,75.59%（542/717）的妇女倾向于接种医疗机构提供的疫苗,24.41%（175/717）的妇女倾向于接种政府或医药公司提供的疫苗。结论河北丰宁地区妇女HPV现患率较高,对HPV及宫颈癌的认知率偏低,宣教后人群认知程度显著提高,因此公众教育可以显著提高人群对HPV疫苗相关知识的认知水平。Objective To evaluate HPV prevalence in women living in Fengning Manchu Autonomous County of Hebei Province, to investigate their awareness and knowledge of cervical cancer, HPV and HPV vaccine and the effect of public education. Methods Cross sectional study and education was conducted to investigate 717 women aged 18～45 years old who living in Fengning. Cervical samples of 647 women were collected for high- risk HPV （HR-HPV） DNA test. Results The overall HRHPV positive rate was 16.07% （104/647）. Among these subjects, 14. 78% （106/717） of them had heard of HPV before education. Awareness of HPV was associated with age, marriage condition, household registration and educational level （P~ 0.05）, and irrelevant to annual household income. 84. 38% （605/717） of them had never received screening. In those who had ever received screening before, 16.07% （18/112） were by classical Pap smear, 39.29% （44/112） by liquid - based cytology, and 8. 04% （9/112） by HPV DNA test. After ducational instruction, HPV cognition rate significant increased （P〈0.05）. 15.76% （113/717） women had heard of HPV vaccine before. 75.59% （542/717） of these women expected medical organization to be the supplier, and the other preferred government or medical companies. Conclusions The level and the knowledge of HPV and cervical cancer is poor. Public health education is necessary to increase the awareness of the population and is essential to the introduction of HPV vaccine.

关 键 词：人乳头瘤病毒 宫颈癌 认知度 疫苗 健康教育 

分 类 号：R737.33[医药卫生—肿瘤]