飞秒激光制瓣LASIK术后不同性别泪膜的变化与分析  

Analysis the changes of tear film after LASIK with corneal flap created by femtosecond laser with the different gender

作　　者：张媛[1] 贾冰冰[1] 张岩[1] 高冬梅[1] 庞玉珍[1] 

机构地区：[1]长春爱尔眼科医院,中国吉林省长春市130002

出　　处：《国际眼科杂志》2014年第8期1461-1463,共3页International Eye Science

摘　　要：目的:观察飞秒激光制瓣LASIK术后不同性别泪膜的变化。方法:收集2013-08/09于我院行飞秒激光制瓣LASIK术并随访3mo的患者120例240眼,将其按性别分为两组,A组:男55例110眼,B组:女65例130眼,观察两组术前、术后1wk;1,2,3mo患者的干眼症状评分、泪膜破裂时间(break-up tear time,BUT)、泪液分泌试验(SchirmerⅠtest,SⅠt)、角膜荧光素染色(corneal fluorescence stain,FL)评分的变化。结果:主观干眼症状评分:两组术后1wk;1,2mo差异有统计学意义(P=0.000,0.023,0.030),术后3mo差异无统计学意义(P=0.283)。BUT:两组术后1wk;1,2,3mo差异有统计学意义(P=0.000,0.017,0.026,0.032)。SⅠt:两组术后1wk;1,2mo差异有统计学意义(P=0.012,0.024,0.018),术后3mo差异无统计学意义(P=0.206)。FL评分:两组术后1wk;1,2,3mo差异有统计学意义(P=0.022,0.015,0.036,0.041)。结论:飞秒激光制瓣LASIK术后泪膜功能的影响男性小于女性。AIM： To observe the changes of tear film on the patients after laser in situ keratomileusis（ LASIK） with corneal flap created by femtosecond laser with the different gender.METHODS： The 120 myopic patients（240 eyes） who underwent femtosecond laser surgery LASIK from August to September 2013 were collected, and these patients were followed up for 3 mo. The patients were divided into two groups according to the gender,group A was male（110 eyes of 55 patients）; group B was female（130 eyes of 65 patients）. Dry eye symptom score,tear break- up time（ BUT）, Schirmer Ⅰ test, corneal fluorescein staining were recorded preoperatively and postoperatively in 1wk,1,2,3mo.RESULTS： Dry eye symptom score： it was statistically significant between two groups after operation in the 1wk,1,2mo（ P = 0. 000,0. 023,0. 030）. It had no statistical significance between the two groups in 3mo（ P = 0. 283）.BUT： it was statistical significance between two groups after operation in the 1wk,1,2,3mo（ P = 0. 000,0. 017,0. 026,0. 032）. Schirmer Ⅰ test： it was statistically significant between two groups after operation in the 1wk,1,2mo（ P = 0. 012,0. 024,0. 018）. It had no statistical significance between the two groups in 3mo（ P = 0. 206）Corneal fluorescein staining： it was statistically significant between two groups after operation in the 1wk,1,2,3mo（P=0.022,0.015,0.036,0.041）. CONCLUSION： The influence of tear film after femtosecond laser surgery for men less than that for women.

关 键 词：飞秒激光 准分子激光原位角膜磨镶术 干眼 泪膜 

分 类 号：R779.63[医药卫生—眼科]