不同程度近视眼角膜前后表面形态学的变化及其相关因素的研究  

Study of the variation of anterior and posterior corneal shape and related factors among various degrees of myopia

作　　者：熊世红[1] 王薇[1] 张帆[1] 陆平[1] 苏红英[1] 

机构地区：[1]首都医科大学附属北京友谊医院,北京100050

出　　处：《中国医刊》2014年第8期59-61,共3页Chinese Journal of Medicine

摘　　要：目的研究不同程度近视眼角膜前后表面形态学的变化。方法收集170例(320只眼)近视眼患者,按近视等效球镜分为三组:低度组86只眼,-1.5D^-3.00D,平均-(2.38±0.53)D;中度组100只眼,-3.38D^-6.00D,平均-(4.77±0.80)D;高度组134只眼,-6.25D^-14.38D,平均-(7.95±1.64)D。使用Pentacam(德国,0CULUS公司)检测,获取角膜前、后表面屈光力。A超测量角膜中央厚度和眼轴长度。所得数据应用SPSS 16.0进行统计学分析。结果低度、中度和高度组角膜前表面屈光度分别为(43.33±1.25)D,(43.90±1.58)D,(44.23±1.43)D;三组角膜后表面屈光度分别为-(6.32±0.21)D,-(6.37±0.23)D,-(6.37±0.23)D。三组之间角膜前后表面屈光度差异无显著性,角膜前表面屈光度与等效球镜有较弱负相关性,而角膜后表面屈光度没有相关性。三组平均角膜厚度分别为(551.6±23.3)μm,(537.0±34.5)μm,(541.2±28.4)μm,差异无显著性。角膜前表面屈光度与眼轴长度有较弱的负相关性,角膜后表面屈光度与眼轴长度有较弱正相关性。结论近视程度对角膜前后表面屈光力没有明显的影响,说明角膜屈光力的改变不是近视发生发展过程中一个主要因素。角膜厚度对角膜前、后表面形态没有影响。随着眼轴的增长角膜前表面相对变平,后表面有前凸趋势。Objective To analyze the variation of anterior and posterior corneal shape among various degrees of my-opic eye. Method We collected 170 subjects（320 eyes） with myopic eye, and we divided them into three groups：mild myopic eye group include 86 eyes,-1. 50D^-3. 00D, mean-（2. 38±0. 53）D;medium myopia eye group in-clude 100 eyes,-3. 38D^-6. 00D,mean-（4. 77±0. 80）D; high myopia eye group include 134 eyes,-6. 25D^-14. 38D,mean -（7. 95±1. 64）D. The anterior curvature and posterior curvature were measured by Pentacam sche-impflug imaging system（ Germany,OCULUS） . The central cornea thickness （ CCT） and axial length were measured by A Scan （France, Quantel）. Then data were analyzed by SPSS 16. 0. Result The anterior corneal refractive power of mild、medium and high myopia is （43. 33±1. 25）D,（43. 90±1. 58）D,（44. 23±1. 43）D;the posterior corneal re-fractive power of them is -（6. 32±0. 21）D, -（6. 37±0. 23）D, -（6. 37±0. 23）D. We found that the anterior and posterior corneal refractive power among the three groups have no statistical significance. The anterior corneal refrac-tive power has weak negtive correlation property with spherical equivalent（ SE） , but no correlation with the posterior corneal refractive power. The mean CCT of the three groups is （551. 6±23. 3）μm, （537. 0±34. 5）μm, （541. 2± 28. 4）μm. We also found the difference had no statistically significance. The anterior corneal refractive power has a weak negative correlation with axial length. Besides the posterior corneal refractive power has a weak positive corre-lation with axial length. Conclusion Myopic degree is not more effect on corneal refractive power, so the change of corneal refractive power is not a important factor during the myopic eye development. Thickness has no impact on the anterior and posterior corneal shape of the cornea. With the axial growth ,the corneal anterior surface is relative-ly flat, and increase trend of forward shift of posterior surface.

关 键 词：近视眼 屈光度 角膜前表面 角膜后表面 角膜厚度 

分 类 号：R770.4[医药卫生—眼科]