药物联合羊膜覆盖术治疗真菌性角膜炎的临床效果  

DRUGS COMBINED WITH AMNIOTIC MEMBRANE COVERING IN THE TREATMENT OF FUNGAL KERATITIS:REPORT OF CLINICAL EFFICACY

作　　者：李青[1] 赵桂秋[1] 林静[1] 王谦[1] 郭彦丽[1] 刘莹[1] 

机构地区：[1]青岛大学附属医院眼科,山东青岛266003

出　　处：《青岛大学医学院学报》2014年第5期383-384,388,共3页Acta Academiae Medicinae Qingdao Universitatis

摘　　要：目的探讨药物联合羊膜覆盖术治疗真菌性角膜炎的临床效果。方法 2006年6月—2013年6月,在我院确诊为真菌性角膜炎的病人97例(98眼),其中单纯药物治疗组53例(53眼),药物联合羊膜覆盖术组44例(45眼)。两组均行角膜溃疡清创术并给予那他霉素滴眼液治疗。药物联合羊膜覆盖术组病人在接受上述处理方法基础上,联合应用羊膜覆盖术治疗。比较两组病人治疗效果、平均视力和平均疗程。结果两组疗效比较,差异有显著性(Uc=2.62,P<0.05)。两组术后平均矫正视力及平均疗程比较,差异有显著性(t=2.07、2.19,P<0.05)。结论药物联合羊膜覆盖术是治疗真菌性角膜溃疡的有效方法,值得临床推广应用。Objective To assess the efficacy of drugs combined with amniotic membrane covering for fungal keratitis. Methods A total of 97 patients （98 eyes） with fungal keratitis were treated in our hospital from June 2006 to June 2013. Of whom, 53 patients （53 eyes） were treated with drugs only, and 44 patients （45 eyes） treated with drugs combined with amniotic membrane covering. All the patients received corneal ulcer debridement and Natamycin eye drops. The patients treated with the combined therapy were given amniotic membrane covering in addition to the above routine management. The efficacy, vision and course of treatment between the two groups were compared. Results The difference of efficacy between the two groups was significant （U=2.62 ,P^0.05）. The differences between the two groups after therapy were significant with regard to both averagely corrected vision and average course of treatment （t=2.07,2.19;P〈0.05）. Conclusion Drugs combined with amniotic membrane covering is an effective method for the treatment of fungal keratitis, which is worthy of clinical application.

关 键 词：羊膜 药物疗法 眼外科手术 角膜炎 眼感染 真菌性 

分 类 号：R772.21[医药卫生—眼科]