定期牙周洁治对固定正畸病人龈下菌斑中具核梭杆菌的影响  

EFFECTS OF REGULAR PERIODONTAL SCALING ON FUSOBACTERIUM NUCLEATUM OF SUBGINGIVAL PLAQUE IN FIXED ORTHODONTIC PATIENTS

作　　者：夏青[1] 白雪雁[2] 于新波[3] 申勇[1] 金娜[1] 范存晖[1] 

机构地区：[1]青岛大学附属医院口腔正畸科,山东青岛266003 [2]滨州医学院附属医院口腔矫形科 [3]青岛大学附属医院口腔内科

出　　处：《青岛大学医学院学报》2014年第5期430-432,共3页Acta Academiae Medicinae Qingdao Universitatis

基　　金：青岛市科技支撑计划项目(06-2-2-6-nsh-2)

摘　　要：目的探讨定期牙周洁治对固定正畸病人龈下菌斑中具核梭杆菌(Fn)的影响。方法选取固定正畸病人48例,随机分为A、B、C共3组,每组16例,牙周洁治周期分别为1、3、6个月,分别于矫治前及矫治1、3、6、9个月时,采用荧光定量PCR法检测各组龈下菌斑中Fn的百分含量。结果 A组和B组矫治1、3、6、9个月时龈下菌斑中Fn的百分含量与矫治前比较差异无显著性(P>0.05),C组在矫治6个月时龈下菌斑中Fn的百分含量较矫治前显著升高(t=2.81,P<0.05)。矫治6个月时,C组龈下菌斑中Fn的百分含量明显高于A组(F=6.62,q=5.14,P<0.05),而其他各组间各时间点龈下菌斑中Fn的百分含量比较差异无显著性(P>0.05)。结论定期牙周洁治对控制固定正畸病人龈下菌斑中Fn的含量具有一定作用。Objective To explore the effects of regular periodontal scaling （RPS） on Fusobacterium nucleatum （Fn） in subgingival plaque in fixed orthodontic patients. Methods Forty-eight fixed orthodontic patients were selected and evenly ran domized to groups A, B and C. The cycles of RPS were one, three and six months, respectively. The percentage of Fn in subgingivai plaque was detected by fluorescence quantitative PCR-1, 3, 6, and 9 months before and after scaling. Results The percentage of Fn markedly increased after scaling than before （t = 2.81, P〈0.05）. In six months of treatment, the percentage of Fn in subgingival plaque in group C was higher than that in group A （F = 6.62,q = 5.14, P〈0.05）, and the differences of Fn between each time point between the other groups were not significant （P〉0.05）. In 1,3,6 and 9 months after treatment, the differences of percentage of Fn in the subgingival plaque in groups A and B were not significant as compared with before treatment （P〉0.05）. In the sixth month of treatment, the percentage of Fn in the group C was significantly higher than that in group A （F=6.62,q=5.14, P〈0.05）, while there were no significant differences between the other groups in different time points （P〉0.05）. Conclusion For fixed orthodontic patients, regular periodontal scaling shows a certain effect on controlling the content of Fn in subgingi val plaque.

关 键 词：牙周洁治 正畸学 矫正 具核梭杆菌 聚合酶链反应 

分 类 号：R781.4[医药卫生—口腔医学] R783.5[医药卫生—临床医学]