苦瓜提取物对四种兽医临床常见菌的抑菌活性研究  

Antibacterial activity of Momordica charantia extract on four common bacteria in veterinary clinical

作　　者：蒋林宏[1] 何利惠 张元丽[1] 贺常亮[1] 

机构地区：[1]四川农业大学动物医院药学系,四川雅安625014

出　　处：《中兽医医药杂志》2014年第4期31-33,共3页Journal of Traditional Chinese Veterinary Medicine

摘　　要：采用打孔法和二倍稀释法研究不同质量浓度的苦瓜提取物对4种临床常见菌的抑制作用,并测定苦瓜提取物对4种菌株生长曲线的影响。结果显示,10 mg/mL的苦瓜提取物对大肠杆菌和沙门氏菌的抑制作用最强,而对链球菌和金黄色葡萄球菌的抑制作用不显著;苦瓜提取物对4种菌株的最小抑菌浓度(MIC)分别为2.5 mg/mL、2.5 mg/mL、5 mg/mL和10 mg/mL。结果提示,苦瓜提取物具有较强的抑菌活性。This paper studied inhibition effects of different concentrations of Momordica charantia extract on four common bacteria in veterinary clinical by using drilling method and double dilution method, and determined their effects on the growth curve of four bacterial strains. The results showed that 10 mg/mL of Momordica chararuia extract exhihit the strongest inhibition on Escherichia coli and Salmonella, but its inhibition on Streptococcus pneumoniae and Staphylococcus aureus was not significant. The minimum inhibitory concentrations （MIC） of Momordica chanuuia extract against four strains was 2.5 mg/mL, 2.5 mg/mL, 5 mg/mL and 10 mg/mL, respectively. These results suggested that Momordica chorantia extract has strong inhibition effect on common bacteria in veterinary clinical.

关 键 词：苦瓜 抑菌活性 最小抑菌浓度 生长曲线 

分 类 号：S853.74[农业科学—临床兽医学]