微创穿刺血肿清除术治疗中等量基底节区脑出血的随机对照研究  

The Randomized Controlled Study of Mini-invasive Aspiration for Middle-volume Spontaneous Basal Ganglia Hemorrhage

作　　者：陈威[1] 易佳[2] 

机构地区：[1]湖北省松滋市人民医院神经内科,湖北松滋434200 [2]湖北省松滋市人民医院CT室,湖北松滋434200

出　　处：《中国医药指南》2014年第23期57-57,59,共2页Guide of China Medicine

摘　　要：目的研究微创穿刺血肿清除术对中等量基底节区脑出血的治疗作用。方法将126例患者随机分入保守治疗(对照组)和微创血肿清除术(观察组)进行治疗。观察两组治疗后第14天时SSS评分及MRS评分,及第90天的MRS评分及BI指数评分及再出血率和病死率。结果治疗14 d时两组SSS评分之间差异有统计学意义(z=5.246,P<0.001),MRS差异无统计学意义(χ2=0.246,P=0.601)。治疗90 d时两组患者MRS及BI评分差异均具有统计学意义(χ2=4.153,P=0.024;t=3.786,P<0.001)。两组患者住院期间均出现再出血及死亡情况,但经比较,两组间差异均无统计学意义(病死率χ2=0.389,P=0.534;再出血率χ2=0.173,P=0.624)。结论与单纯的保守治疗相比,微创血肿清除术治疗中等量基底节区脑出血可明显提高患者的日常生活活动能力,进而降低致残率和依赖生存率,且不增加再出血率和病死率,是一项安全有效的治疗方法。Objective To study the effect of mini-invasive aspiration for middle-volume spontaneous basal ganglia hemorrhage. Methods 126 patients were randomly divided into control group and observer group. The SSS score and MRS score in the14th day, MRS score, BI score, the rebleeding rate and mortality in the 90th day after treatment were used as the evaluating parameters. Results No difference was found between the two groups in 14th day MRS score（χ^2=0.246, P=0.601）, the rebleeding rate and mortality in the 90th day（z2=0.389, P=-0.534; Z2=0.173, P=0.624）, and there are obviously difference in 14th day SSS score（z=5.246, P〈0.001）, MRS score, BI score in the 90th day（χ^2=4.153,P=-0.024; t=3.786, P〈0.001）. Conclusion Compared With basal ganglia intracerebral hemorrhage, the mini-invasive aspiration remarkably improves the patients activities of daily life, deceases their dependency and disability rates, indicating that the mini-invasive aspiration is a safe and effective method.

关 键 词：微创穿刺血肿清除术 中等量出血 基底节 脑出血 

分 类 号：R743.34[医药卫生—神经病学与精神病学]